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Bisoprolol/Hydrochlorothiazide

Brand names: Bisoprolol-Hydrochlorothiazide

Thiazide Diuretic Oral

At a glance

Medicare prescriptions, 2024
311,476
Medicare drug cost
$8.6M
Average cost per prescription
$27.57
Clinicians who prescribed it
12,324

Where it is prescribed

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List the prescribers in any state, county, city or ZIP code →

What it is used for

Bisoprolol fumarate and hydrochlorothiazide tablets are indicated in the management of hypertension.

From the FDA-approved prescribing information (label dated August 2026). Full labels on DailyMed (opens in a new tab)

Who prescribes it

All prescribers, by place, name or specialty →

Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.

Trend, 2019–2024

Medicare prescriptions fell 20% from 2019 to 2024.

Medicare Part D prescriptions per year, all prescribers
  • 2019713,940
  • 2020685,968
  • 2021646,360
  • 2022614,876
  • 2023581,797
  • 2024568,126

Biggest change by state since 2019

  • Florida −12%
  • Arizona −13%
  • Maryland −14%
  • California −15%
  • Louisiana −17%
  • Nebraska (smallest change) −30%
  • Arkansas (smallest change) −29%

From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.

What it looks like

Pills from 1 maker on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.

Edenbridge Pharmaceuticals LLC.

StrengthLooks likeImprint
2.5 mg / 6.25 mg hydrochlorothiazideyellow round tablet, 7 mm920
5 mg / 6.25 mg hydrochlorothiazidepink round tablet, 7 mm921
10 mg / 6.25 mg hydrochlorothiazidewhite round tablet, 7 mm922

Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.

Industry payments about this drug

No industry payments to clinicians named this drug in 2025.

Recalls and shortages

Not on the FDA drug shortage list.

2 recalls since 2020

  • Jan 2026 · Unichem Pharmaceuticals USA Inc. · Class II
    cGMP Deviations: recall due to not meeting the N-Nitroso Bisoprolol impurity specification limits.
  • Mar 2021 · Cardinal Health Inc. · Class II
    CGMP Deviations: Intermittent exposure to temperature excursion during storage.

See all recalls →

Recalls usually affect specific lots from one maker, not every version of a drug. Class I is the most serious; most drug recalls are Class II. FDA recalls (opens in a new tab)

Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.