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Butalb/Acetaminophen/Caffeine

Brand names: Butalbital-Acetaminophen-Caffe, Esgic, Fioricet

At a glance

Medicare prescriptions, 2024
493,310
Medicare drug cost
$15.1M
Average cost per prescription
$30.61
Clinicians who prescribed it
20,924

Where it is prescribed

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List the prescribers in any state, county, city or ZIP code →

Trend, 2019–2024

Medicare prescriptions rose 3% from 2019 to 2024.

Medicare Part D prescriptions per year, all prescribers
  • 2019759,222
  • 2020807,148
  • 2021781,476
  • 2022779,916
  • 2023769,924
  • 2024778,395

Biggest change by state since 2019

  • Louisiana +69%
  • Mississippi +39%
  • South Carolina +25%
  • Virginia +21%
  • North Carolina +21%
  • Pennsylvania (smallest change) −24%
  • New York (smallest change) −23%

From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.

Industry payments about this drug

No industry payments to clinicians named this drug in 2025.

Recalls and shortages

Not on the FDA drug shortage list.

No FDA-reported recalls since 2020.

Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.