Chlorthalidone
Brand names: Chlorthalidone, Thalitone
At a glance
- Medicare prescriptions, 2024
- 2,218,535
- Medicare drug cost
- $36.0M
- Average cost per prescription
- $16.24
- Clinicians who prescribed it
- 78,754
Where it is prescribed
List the prescribers in any state, county, city or ZIP code →
What it is used for
THALITONE is a thiazide-like diuretic indicated: • For the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. • as adjunctive therapy in edema associated with heart failure, cirrhosis of the liver, and renal disease, including nephrotic syndrome.
From the FDA-approved prescribing information (label dated June 2026). Full labels on DailyMed (opens in a new tab)
Who prescribes it
- Family Medicine 31.1%
- Internal Medicine 24.8%
- Nurse Practitioners 14.5%
- Cardiology 10.1%
- Nephrology (Kidney) 6.3%
- Physician Assistants 4.6%
- Interventional Cardiology 3.3%
- General Practice 1.3%
- Geriatric Medicine 0.9%
- Endocrinology & Diabetes 0.4%
- Hospitalist 0.3%
- Cardiac Electrophysiology 0.3%
All prescribers, by place, name or specialty →
Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.
Trend, 2019–2024
Medicare prescriptions rose 25% from 2019 to 2024.
Biggest change by state since 2019
- Puerto Rico +71%
- North Dakota +52%
- Maine +50%
- Idaho +49%
- Florida +41%
- New York (smallest change) +4%
- Massachusetts (smallest change) +10%
From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.
What it looks like
Pills from 5 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.
Casper Pharma LLC
| Strength | Looks like | Imprint |
|---|---|---|
| 15 mg | white freeform tablet, 7 mm | L 96 |
| 25 mg | white freeform tablet, 9 mm | L 99 |
Marlex Pharmaceuticals, Inc
| Strength | Looks like | Imprint |
|---|---|---|
| 25 mg / 50 mg atenolol | white round tablet, 8 mm, scored to split in 2 | N 390 |
| 100 mg / 25 mg chlorthalidone | white round tablet, 10 mm | N 391 |
Nivagen Pharmaceuticals, Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 25 mg | yellow round tablet, 6 mm | N |
| 50 mg | green round tablet, 7 mm, scored to split in 2 | N |
Pd-Rx Pharmaceuticals, Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 25 mg | yellow round tablet, 7 mm | MP 30 |
| 50 mg | green round tablet, 7 mm | MP 43 |
Umedica Laboratories USA Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 25 mg | yellow round tablet, 7 mm | N |
| 50 mg | green round tablet, 7 mm, scored to split in 2 | N |
Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.
Industry payments about this drug
No industry payments to clinicians named this drug in 2025.
Recalls and shortages
Not on the FDA drug shortage list.
5 recalls since 2020
- Sep 2026 · Inventia Healthcare Limited · Class II
Failed Dissolution Specifications - Jun 2026 · Inventia Healthcare Limited · Class II
Failed Dissolution Specifications - May 2025 · Avkare · Class II
Failed Dissolution Specifications - Feb 2022 · Sun Pharmaceutical Industries Inc · Class II
Foreign Matter identified as stainless steel microscopic wear particles mixed with punch lubricant oil and silicone particles from the dust cup - Jan 2022 · Cardinal Healthcare · Class II
CGMP Deviations: Products were exposed to temperatures outside of the products labeled storage conditions.
Recalls usually affect specific lots from one maker, not every version of a drug. Class I is the most serious; most drug recalls are Class II. FDA recalls (opens in a new tab)
Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.