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Dronedarone Hcl

Brand names: Multaq

Antiarrhythmic Oral

At a glance

Medicare prescriptions, 2024
223,878
Medicare drug cost
$278.1M
Average cost per prescription
$1,242
Clinicians who prescribed it
7,785

Where it is prescribed

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List the prescribers in any state, county, city or ZIP code →

What it is used for

MULTAQ ® is indicated to reduce the risk of hospitalization for atrial fibrillation in patients in sinus rhythm with a history of paroxysmal or persistent atrial fibrillation (AF).

From the FDA-approved prescribing information (label dated May 2025). Full labels on DailyMed (opens in a new tab)

Boxed warning

WARNING: INCREASED RISK OF DEATH, STROKE AND HEART FAILURE IN PATIENTS WITH DECOMPENSATED HEART FAILURE OR PERMANENT ATRIAL FIBRILLATION In patients with symptomatic heart failure and recent decompensation requiring hospitalization or NYHA Class IV heart failure, MULTAQ doubles the risk of death. MULTAQ is contraindicated in patients with symptomatic heart failure with recent decompensation requiring hospitalization or NYHA Class IV heart failure. In patients with permanent atrial fibrillation, MULTAQ doubles the risk of death, stroke and hospitalization for heart failure. MULTAQ is contraindicated in patients in atrial fibrillation (AF) who will not or cannot be cardioverted into normal sinus rhythm.

The FDA’s strongest warning on a label. It doesn’t mean the drug is unsafe for most people; talk to your doctor or pharmacist before stopping or changing any medicine.

Who prescribes it

All prescribers, by place, name or specialty →

Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.

Trend, 2019–2024

Medicare prescriptions fell 7% from 2019 to 2024.

Medicare Part D prescriptions per year, all prescribers
  • 2019341,247
  • 2020329,124
  • 2021317,680
  • 2022312,507
  • 2023310,777
  • 2024318,700

Biggest change by state since 2019

  • New York +22%
  • New Jersey +11%
  • Arkansas +9%
  • California +3%
  • Alabama −2%
  • Tennessee (smallest change) −30%
  • Missouri (smallest change) −28%

From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.

What it looks like

Pills from 2 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.

Cardinal Health 107, LLC

StrengthLooks likeImprint
400 mgwhite oval tablet, 17 mm4142

Sanofi-Aventis U.S. LLC

StrengthLooks likeImprint
400 mgwhite oval tablet, 17 mm4142

Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.

Industry payments about this drug

Drug makers reported $7,724 in payments to clinicians that named this drug in 2025 (meals, speaking, consulting and similar).

  • Sanofi US Services Inc. $7,408
  • Sanofi-aventis U.S. LLC $316

See all companies →

Source: CMS Open Payments, general payments (not research), program year 2025. A payment is not evidence of wrongdoing. Payments by doctor

Recalls and shortages

Not on the FDA drug shortage list.

No FDA-reported recalls since 2020.

Industry-funded trials

Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.