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Epinephrine

Brand names: Auvi-Q, Epinephrine, Adrenalin

alpha-Adrenergic Agonist, beta-Adrenergic Agonist, Catecholamine Intramuscular, intravenous, subcutaneous

At a glance

Medicare prescriptions, 2024
137,230
Medicare drug cost
$28.1M
Average cost per prescription
$205
Clinicians who prescribed it
6,257

Where it is prescribed

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List the prescribers in any state, county, city or ZIP code →

What it is used for

Adrenalin ® is a non-selective alpha and beta adrenergic agonist indicated for: Emergency treatment of allergic reactions (Type 1), including anaphylaxis To increase mean arterial blood pressure in adult patients with hypotension associated with septic shock 1.1 Anaphylaxis Emergency treatment of allergic reactions (Type I), including anaphylaxis, which may result from insect stings or bites, foods, drugs, sera, diagnostic testing substances and other allergens, as well as idiopathic anaphylaxis or exercise-induced anaphylaxis.

From the FDA-approved prescribing information (label dated June 2026). Full labels on DailyMed (opens in a new tab)

Who prescribes it

All prescribers, by place, name or specialty →

Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.

Trend, 2019–2024

Medicare prescriptions rose 89% from 2019 to 2024.

Medicare Part D prescriptions per year, all prescribers
  • 2019309,012
  • 2020344,338
  • 2021452,144
  • 2022425,462
  • 2023522,510
  • 2024582,724

Biggest change by state since 2019

  • Indiana +102%
  • Florida +100%
  • Ohio +99%
  • Virginia +96%
  • Georgia +94%
  • Massachusetts (smallest change) +72%
  • Minnesota (smallest change) +73%

From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.

Industry payments about this drug

Drug makers reported $2.4M in payments to clinicians that named this drug in 2025 (meals, speaking, consulting and similar).

  • Ars Pharmaceuticals Operations, Inc. $2.1M
  • Kaleo, Inc. $169,311
  • Alk-abello, Inc $121,114

See all companies →

Source: CMS Open Payments, general payments (not research), program year 2025. A payment is not evidence of wrongdoing. Payments by doctor

Recalls and shortages

Not on the FDA drug shortage list.

8 recalls since 2020

  • Aug 2026 · American Regent, Inc. · Class I
    Presence of Particulate Matter and Lack of Assurance of Sterility. Particulate matter identified as nylon, cellulosic, acrylic, polyethylene and glass and broken and leaking vials.
  • May 2026 · Fresenius Kabi USA, LLC · Class III
    Failed Impurities/Degradations Specifications
  • Mar 2026 · International Medication Systems Ltd. · Class II
    Lack of Assurance of Sterility
  • Jan 2024 · Henry Schein Inc. and Glove Club Hsi Gloves Inc. · Class II
    Labeling: Incorrect or Missing Lot and/or Exp Date. The expiration date listed on the Repack Pouch Label is incorrect.
  • Mar 2023 · Focus Health Group Inc · Class III
    Labeling; Incorrect NDC number on outer carton of product.
  • Apr 2022 · McKesson Medical-Surgical Inc. Corporate Office · Class II
    cGMP deviations: Temperature abuse
  • Mar 2021 · Cardinal Health Inc. · Class II
    CGMP Deviations: Intermittent exposure to temperature excursion during storage.
  • Mar 2020 · Teva Pharmaceuticals USA · Class II
    CGMP Deviations: Precautions taken due to Out-of-specification for trigger force for a non-marketed lot number that shares the same component.

See all recalls →

Recalls usually affect specific lots from one maker, not every version of a drug. Class I is the most serious; most drug recalls are Class II. FDA recalls (opens in a new tab)

Industry-funded trials

Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.