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Hydrochlorothiazide

Brand names: Hydrochlorothiazide

Thiazide Diuretic Oral

At a glance

Medicare prescriptions, 2024
17,568,356
Medicare drug cost
$77.4M
Average cost per prescription
$4.41
Clinicians who prescribed it
244,479

Where it is prescribed

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List the prescribers in any state, county, city or ZIP code →

What it is used for

Hydrochlorothiazide tablets are indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Hydrochlorothiazide tablets have also been found useful in edema due to various forms of renal dysfunction such as nephrotic syndrome, acute glomerulonephritis, and chronic renal failure.

From the FDA-approved prescribing information (label dated July 2026). Full labels on DailyMed (opens in a new tab)

Who prescribes it

All prescribers, by place, name or specialty →

Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.

Trend, 2019–2024

Medicare prescriptions rose 3% from 2019 to 2024.

Medicare Part D prescriptions per year, all prescribers
  • 201917,884,835
  • 202019,756,740
  • 202118,791,083
  • 202218,587,909
  • 202318,347,405
  • 202418,456,721

Biggest change by state since 2019

  • Utah +20%
  • Puerto Rico +16%
  • Delaware +15%
  • North Dakota +14%
  • Nevada +12%
  • Massachusetts (smallest change) −10%
  • California (smallest change) −6%

From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.

What it looks like

Pills from 5 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.

A-S Medication Solutions

StrengthLooks likeImprint
12.5 mgorange round tablet, 5 mmH 1
25 mgorange round tablet, 6 mm, scored to split in 2H 2
50 mgorange round tablet, 8 mm, scored to split in 2H 3

Bryant Ranch Prepack

StrengthLooks likeImprint
25 mg / 100 mg losartan potassiumyellow tear tablet, 15 mmLU M43

Chartwell Rx, LLC

StrengthLooks likeImprint
12.5 mgorange round tablet, 6 mmA 1
25 mgorange round tablet, 6 mmH 2
50 mgorange round tablet, 8 mmH 3

Pd-Rx Pharmaceuticals, Inc.

StrengthLooks likeImprint
25 mgorange round tablet, 6 mm, scored to split in 2TEVA 2083

Redpharm Drug

StrengthLooks likeImprint
25 mgorange round tablet, 6 mm, scored to split in 2TEVA 2083

Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.

Industry payments about this drug

No industry payments to clinicians named this drug in 2025.

Recalls and shortages

Not on the FDA drug shortage list.

No FDA-reported recalls since 2020.

Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.