Isosorbide Dinitrate
Brand names: Isordil, Isosorbide Dinitrate
At a glance
- Medicare prescriptions, 2024
- 279,564
- Medicare drug cost
- $13.5M
- Average cost per prescription
- $48.33
- Clinicians who prescribed it
- 11,853
Where it is prescribed
List the prescribers in any state, county, city or ZIP code →
What it is used for
Isosorbide dinitrate tablets are indicated for the prevention of angina pectoris due to coronary artery disease. The onset of action of immediate-release oral isosorbide dinitrate is not sufficiently rapid for this product to be useful in aborting an acute anginal episode.
From the FDA-approved prescribing information (label dated July 2026). Full labels on DailyMed (opens in a new tab)
Who prescribes it
- Internal Medicine 24.0%
- Cardiology 20.6%
- Family Medicine 18.1%
- Nurse Practitioners 14.7%
- Interventional Cardiology 7.2%
- General Practice 3.4%
- Physician Assistants 2.8%
- Geriatric Medicine 2.5%
- Heart Failure & Transplant Cardiology 1.7%
- Nephrology (Kidney) 1.1%
- Hospitalist 1.0%
- Cardiac Electrophysiology 0.5%
All prescribers, by place, name or specialty →
Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.
Trend, 2019–2024
Medicare prescriptions fell 10% from 2019 to 2024.
Biggest change by state since 2019
- Florida +13%
- Arizona +8%
- Oklahoma +7%
- Georgia +1%
- Indiana −0%
- Massachusetts (smallest change) −28%
- Iowa (smallest change) −26%
From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.
What it looks like
Pills from 4 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.
Avpak
| Strength | Looks like | Imprint |
|---|---|---|
| 5 mg | white round tablet, 8 mm, scored to split in 2 | PAR 020 |
| 10 mg | white round tablet, 8 mm, scored to split in 2 | PAR 021 |
| 20 mg | green round tablet, 8 mm, scored to split in 2 | PAR 022 |
Cardinal Health 107, LLC
| Strength | Looks like | Imprint |
|---|---|---|
| 10 mg | white round tablet, 8 mm, scored to split in 2 | WW 771 |
| 20 mg | green round tablet, 8 mm, scored to split in 2 | WW 772 |
Major Pharmaceuticals
| Strength | Looks like | Imprint |
|---|---|---|
| 10 mg | white round tablet, 8 mm, scored to split in 2 | WW 771 |
| 20 mg | green round tablet, 8 mm, scored to split in 2 | WW 772 |
Par Health USA, LLC
| Strength | Looks like | Imprint |
|---|---|---|
| 5 mg | white round tablet, 8 mm, scored to split in 2 | PAR 020 |
| 10 mg | white round tablet, 8 mm, scored to split in 2 | PAR 021 |
| 20 mg | green round tablet, 8 mm, scored to split in 2 | PAR 022 |
| 30 mg | blue round tablet, 8 mm, scored to split in 2 | PAR 009 |
Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.
Industry payments about this drug
No industry payments to clinicians named this drug in 2025.
Recalls and shortages
Not on the FDA drug shortage list.
No FDA-reported recalls since 2020.
Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.