Levetiracetam
Brand names: Keppra Xr, Levetiracetam Er, Roweepra, Spritam, Keppra, Levetiracetam
At a glance
- Medicare prescriptions, 2024
- 3,983,233
- Medicare drug cost
- $180.3M
- Average cost per prescription
- $45.26
- Clinicians who prescribed it
- 77,024
Where it is prescribed
List the prescribers in any state, county, city or ZIP code →
What it is used for
Levetiracetam extended-release tablets are indicated for the treatment of partial-onset seizures in patients 12 years of age and older.
From the FDA-approved prescribing information (label dated August 2026). Full labels on DailyMed (opens in a new tab)
Who prescribes it
- Neurology 29.3%
- Internal Medicine 20.8%
- Family Medicine 18.8%
- Nurse Practitioners 16.7%
- Physician Assistants 4.4%
- Geriatric Medicine 2.8%
- General Practice 1.6%
- Hospitalist 1.0%
- Physical Medicine & Rehabilitation (PM&R) 0.5%
- Psychiatry 0.4%
- Child Neurology 0.4%
- Emergency Medicine 0.2%
All prescribers, by place, name or specialty →
Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.
Trend, 2019–2024
Medicare prescriptions rose 7% from 2019 to 2024.
Biggest change by state since 2019
- Montana +28%
- Kansas +25%
- West Virginia +18%
- Alabama +17%
- Vermont +17%
- California (smallest change) −4%
- District of Columbia (smallest change) −3%
From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.
What it looks like
Pills from 3 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.
Direct_rx
| Strength | Looks like | Imprint |
|---|---|---|
| 250 mg | pink oval tablet, 14 mm, scored to split in 2 | SLC 221 |
Pd-Rx Pharmaceuticals, Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 500 mg | yellow oval tablet, 16 mm, scored to split in 2 | 500 MG 1015 |
Remedyrepack Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 500 mg | white oval tablet, 19 mm | SG 189 |
Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.
Industry payments about this drug
No industry payments to clinicians named this drug in 2025.
Recalls and shortages
Not on the FDA drug shortage list.
1 recall since 2020
- Mar 2020 · Aurobindo Pharma USA Inc. · Class II
CGMP Deviations: Products were manufactured in a processing area in which water leakage was observed
Recalls usually affect specific lots from one maker, not every version of a drug. Class I is the most serious; most drug recalls are Class II. FDA recalls (opens in a new tab)
Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.