Lisinopril
Brand names: Qbrelis, Zestril, Lisinopril
At a glance
- Medicare prescriptions, 2024
- 35,032,109
- Medicare drug cost
- $246.2M
- Average cost per prescription
- $7.03
- Clinicians who prescribed it
- 305,164
Where it is prescribed
List the prescribers in any state, county, city or ZIP code →
What it is used for
Zestril is an angiotensin converting enzyme (ACE) inhibitor indicated for: Treatment of hypertension in adults and pediatric patients 6 years of age and older Adjunct therapy for heart failure Treatment of Acute Myocardial Infarction
From the FDA-approved prescribing information (label dated January 2025). Full labels on DailyMed (opens in a new tab)
Boxed warning
WARNING: FETAL TOXICITY When pregnancy is detected, discontinue ZESTRIL as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus. WARNING: FETAL TOXICITY See full prescribing information for complete boxed warning. When pregnancy is detected, discontinue Zestril as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus.
The FDA’s strongest warning on a label. It doesn’t mean the drug is unsafe for most people; talk to your doctor or pharmacist before stopping or changing any medicine.
Who prescribes it
- Family Medicine 35.3%
- Internal Medicine 24.1%
- Nurse Practitioners 19.1%
- Physician Assistants 6.6%
- Cardiology 5.4%
- Interventional Cardiology 1.9%
- General Practice 1.8%
- Nephrology (Kidney) 1.4%
- Geriatric Medicine 1.2%
- Endocrinology & Diabetes 0.6%
- Hospitalist 0.4%
- Cardiac Electrophysiology 0.3%
All prescribers, by place, name or specialty →
Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.
Trend, 2019–2024
Medicare prescriptions fell 3% from 2019 to 2024.
Biggest change by state since 2019
- Utah +12%
- Maine +12%
- New Hampshire +11%
- Idaho +11%
- Puerto Rico +10%
- Mississippi (smallest change) −20%
- District of Columbia (smallest change) −18%
From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.
What it looks like
Pills from 5 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.
Almatica Pharma Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 10 mg / 12.5 mg hydrochlorothiazide | pink round tablet, 6 mm | ZESTORETIC 141 |
| 20 mg / 12.5 mg hydrochlorothiazide | white round tablet, 8 mm | ZESTORETIC 142 |
| 20 mg / 25 mg hydrochlorothiazide | pink round tablet, 8 mm | ZESTORETIC 145 |
Coupler LLC
| Strength | Looks like | Imprint |
|---|---|---|
| 12.5 mg / 10 mg lisinopril | blue hexagon (6 sided) tablet, 7 mm | LL B01 |
Pd-Rx Pharmaceuticals, Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 5 mg | yellow capsule, 8 mm | H 145 |
Remedyrepack Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 10 mg | pink round tablet, 8 mm | LUPIN 10 |
Upsher-Smith Laboratories, LLC
| Strength | Looks like | Imprint |
|---|---|---|
| 2.5 mg | white round tablet, 7 mm | ZESTRIL 2 1 2 135 |
| 5 mg | pink capsule, 8 mm, scored to split in 2 | ZESTRIL 130 |
| 10 mg | pink round tablet, 8 mm | ZESTRIL10 131 |
| 20 mg | red round tablet, 8 mm | ZESTRIL20 132 |
| 30 mg | red round tablet, 9 mm | ZESTRIL30 133 |
| 40 mg | yellow round tablet, 8 mm | ZESTRIL40 134 |
Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.
Industry payments about this drug
No industry payments to clinicians named this drug in 2025.
Recalls and shortages
Not on the FDA drug shortage list.
5 recalls since 2020
- Nov 2024 · Evaric Pharmaceuticals Inc. · Class II
Presence of Foreign Object: A pharmacist discovered a metal fragment embedded in a lisinopril 10 mg tablet. - Oct 2023 · Ncs Healthcare of Kentucky Inc · Class III
Presence of Foreign Tablets: Potential of stray tablet(s) of Amlodipine Besylate 10 mg Tablet within the recalled lots - Sep 2022 · Lupin Pharmaceuticals Inc. · Class II
Presence of Foreign Substance: Foreign material (metal piece) embedded in one tablet. - May 2020 · Lupin Pharmaceuticals Inc. · Class II
Product Mix Up: Lisinopril 10 mg tablets were found in Lisinopril 5 mg 1000-count bottle. - Mar 2020 · Lupin Pharmaceuticals Inc. · Class II
Presence of Foreign Tablet/ Capsule: Product complaint received indicating mix-up of one lisinopril 5mg tablet inside of a 30 mg, 100-count bottle of Lisinopril Tablets.
Recalls usually affect specific lots from one maker, not every version of a drug. Class I is the most serious; most drug recalls are Class II. FDA recalls (opens in a new tab)
Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.