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Nabumetone

Brand names: Nabumetone, Relafen Ds

Nonsteroidal Anti-inflammatory Drug Oral

At a glance

Medicare prescriptions, 2024
395,874
Medicare drug cost
$7.0M
Average cost per prescription
$17.76
Clinicians who prescribed it
12,520

Where it is prescribed

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List the prescribers in any state, county, city or ZIP code →

What it is used for

Carefully consider the potential benefits and risks of nabumetone tablets and other treatment options before deciding to use nabumetone tablets. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals. Nabumetone tablets are indicated for relief of signs and symptoms of osteoarthritis and rheumatoid arthritis

From the FDA-approved prescribing information (label dated January 2024). Full labels on DailyMed (opens in a new tab)

Boxed warning

Cardiovascular Risk Nonsteroidal anti-inflammatory drugs (NSAIDs Throughout this package insert, the term NSAID refers to a non-aspirin non-steroidal anti-inflammatory drug. ) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use. Nabumetone is contraindicated in the setting of coronary artery bypass graft (CABG) surgery. Gastrointestinal Risk NSAIDs cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients are at greater risk for serious gastrointestinal events.

The FDA’s strongest warning on a label. It doesn’t mean the drug is unsafe for most people; talk to your doctor or pharmacist before stopping or changing any medicine.

Who prescribes it

All prescribers, by place, name or specialty →

Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.

Trend, 2019–2024

Medicare prescriptions fell 21% from 2019 to 2024.

Medicare Part D prescriptions per year, all prescribers
  • 2019735,204
  • 2020702,425
  • 2021669,478
  • 2022640,659
  • 2023610,361
  • 2024584,185

Biggest change by state since 2019

  • Texas +7%
  • New Jersey +2%
  • Louisiana −0%
  • Arizona −2%
  • Florida −6%
  • Massachusetts (smallest change) −38%
  • Oregon (smallest change) −35%

From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.

What it looks like

Pills from 4 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.

Carwin Pharmaceutical Associates, LLC

StrengthLooks likeImprint
1000 mgwhite oval tablet, 19 mmNB 1000

Pd-Rx Pharmaceuticals, Inc.

StrengthLooks likeImprint
750 mgwhite oval tablet, 19 mmSG 466

Sportpharm LLC

StrengthLooks likeImprint
500 mgwhite oval tablet, 16 mmSG 465
750 mgwhite oval tablet, 19 mmSG 466

St. Mary's Medical PArk Pharmacy

StrengthLooks likeImprint
750 mgwhite oval tablet, 19 mmSG 466

Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.

Industry payments about this drug

No industry payments to clinicians named this drug in 2025.

Recalls and shortages

Not on the FDA drug shortage list.

No FDA-reported recalls since 2020.

Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.