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Naltrexone Hcl

Brand names: Naltrexone Hcl

Opioid Antagonist Oral

Part of: Opioid addiction treatment

At a glance

Medicare prescriptions, 2024
231,350
Medicare drug cost
$11.4M
Average cost per prescription
$49.26
Clinicians who prescribed it
10,378

Where it is prescribed

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List the prescribers in any state, county, city or ZIP code →

What it is used for

Naltrexone Hydrochloride Tablets, USP are indicated in the treatment of alcohol dependence and for the blockade of the effects of exogenously administered opioids. Naltrexone Hydrochloride Tablets, USP have not been shown to provide any therapeutic benefit except as part of an appropriate plan of management for the addictions.

From the FDA-approved prescribing information (label dated September 2026). Full labels on DailyMed (opens in a new tab)

Who prescribes it

All prescribers, by place, name or specialty →

Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.

Trend, 2019–2024

Medicare prescriptions rose 91% from 2019 to 2024.

Medicare Part D prescriptions per year, all prescribers
  • 2019243,866
  • 2020267,908
  • 2021298,064
  • 2022332,344
  • 2023395,403
  • 2024465,823

Biggest change by state since 2019

  • Virginia +131%
  • Minnesota +119%
  • Washington +112%
  • Michigan +112%
  • Wisconsin +111%
  • Oklahoma (smallest change) +41%
  • Massachusetts (smallest change) +50%

From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.

What it looks like

Pills from 1 maker on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.

Specgx LLC

StrengthLooks likeImprint
50 mgyellow oval tablet, 13 mm, scored to split in 25 0 1170

Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.

Industry payments about this drug

No industry payments to clinicians named this drug in 2025.

Recalls and shortages

Not on the FDA drug shortage list.

1 recall since 2020

  • Apr 2022 · McKesson Medical-Surgical Inc. Corporate Office · Class II
    cGMP deviations: Temperature abuse

See all recalls →

Recalls usually affect specific lots from one maker, not every version of a drug. Class I is the most serious; most drug recalls are Class II. FDA recalls (opens in a new tab)

Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.