Nitrofurantoin Monohyd/M-Cryst
Brand names: Macrobid, Nitrofurantoin Mono-Macro
Part of: Common antibiotics
At a glance
- Medicare prescriptions, 2024
- 2,972,015
- Medicare drug cost
- $45.2M
- Average cost per prescription
- $15.21
- Clinicians who prescribed it
- 112,350
Where it is prescribed
List the prescribers in any state, county, city or ZIP code →
What it is used for
Nitrofurantoin capsules (macrocrystals) are specifically indicated for the treatment of urinary tract infections when due to susceptible strains of Escherichia coli, enterococci, Staphylococcus aureus, and certain susceptible strains of Klebsiella and Enterobacter species.
From the FDA-approved prescribing information (label dated June 2026). Full labels on DailyMed (opens in a new tab)
Who prescribes it
- Nurse Practitioners 29.8%
- Family Medicine 22.3%
- Internal Medicine 16.1%
- Physician Assistants 12.4%
- Urology 9.6%
- Urogynecology 2.1%
- Emergency Medicine 2.0%
- OB-GYN (Obstetrics & Gynecology) 2.0%
- General Practice 0.9%
- Geriatric Medicine 0.8%
- Nephrology (Kidney) 0.3%
- Infectious Disease 0.2%
All prescribers, by place, name or specialty →
Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.
Trend, 2019–2024
Medicare prescriptions rose 44% from 2019 to 2024.
Biggest change by state since 2019
- Puerto Rico +145%
- Tennessee +68%
- Florida +57%
- Arkansas +55%
- Idaho +54%
- West Virginia (smallest change) +24%
- North Dakota (smallest change) +25%
From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.
What it looks like
Pills from 1 maker on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.
Bluepoint Laboratories
| Strength | Looks like | Imprint |
|---|---|---|
| 25 mg | white capsule, 11 mm | LS 410 |
| 50 mg | white capsule, 16 mm | LS 411 |
| 100 mg | blue capsule, 18 mm | LS 412 |
Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.
Industry payments about this drug
No industry payments to clinicians named this drug in 2025.
Recalls and shortages
Not on the FDA drug shortage list.
1 recall since 2020
- Jul 2024 · Sun Pharmaceutical Industries Inc · Class II
Failed Dissolution Specifications
Recalls usually affect specific lots from one maker, not every version of a drug. Class I is the most serious; most drug recalls are Class II. FDA recalls (opens in a new tab)
Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.