Omeprazole
Brand names: Omeprazole
At a glance
- Medicare prescriptions, 2024
- 27,648,060
- Medicare drug cost
- $351.9M
- Average cost per prescription
- $12.73
- Clinicians who prescribed it
- 281,480
Where it is prescribed
List the prescribers in any state, county, city or ZIP code →
What it is used for
Omeprazole is a proton pump inhibitor (PPI) indicated for the: Treatment of active duodenal ulcer in adults Eradication of Helicobacter pylori to reduce the risk of duodenal ulcer recurrence in adults Treatment of active benign gastric ulcer in adults Treatment of symptomatic gastroesophageal reflux disease (GERD) in patients 2 years of age and older Maintenance of healing of EE due to acid-mediated GERD in patients 2 years of age and older Pathologic hypersecretory conditions in adults
From the FDA-approved prescribing information (label dated June 2026). Full labels on DailyMed (opens in a new tab)
Who prescribes it
- Family Medicine 33.6%
- Internal Medicine 24.9%
- Nurse Practitioners 19.2%
- Physician Assistants 7.2%
- Gastroenterology 6.4%
- General Practice 1.9%
- Geriatric Medicine 1.2%
- ENT (Otolaryngology) 0.8%
- Cardiology 0.5%
- Pulmonology 0.5%
- Hospitalist 0.4%
- General Surgery 0.3%
All prescribers, by place, name or specialty →
Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.
Trend, 2019–2024
Medicare prescriptions rose 3% from 2019 to 2024.
Biggest change by state since 2019
- Delaware +21%
- Montana +20%
- Maine +18%
- Idaho +18%
- New Hampshire +17%
- New Mexico (smallest change) −8%
- Mississippi (smallest change) −8%
From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.
What it looks like
Pills from 5 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.
Amazon.com Services LLC
| Strength | Looks like | Imprint |
|---|---|---|
| 20 mg | red round tablet, 9 mm | 20 |
Cardinal Health 107, LLC
| Strength | Looks like | Imprint |
|---|---|---|
| 20 mg | white capsule, 11 mm | ZA 10 20MG |
H E B
| Strength | Looks like | Imprint |
|---|---|---|
| 20 mg | brown oval tablet, 12 mm | 20 |
Meijer, Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 20 mg | orange capsule, 14 mm | 24S |
Qpharma Inc
| Strength | Looks like | Imprint |
|---|---|---|
| 20 mg | pink capsule, 19 mm | E 67 |
Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.
Industry payments about this drug
No industry payments to clinicians named this drug in 2025.
Recalls and shortages
Not on the FDA drug shortage list.
2 recalls since 2020
- Jun 2025 · Dr. Reddy's Laboratories, Inc. · Class II
Presence of foreign tablets/capsules: presence of foreign Divalproex Sodium Extended-Release 250mg tablet in a bottle of omeprazole capsules. - Oct 2021 · Dr. Reddy's Laboratories, Inc. · Class II
CGMP Deviations: Customer complaint for the presence of a staple co-mingled with capsules within the bottle.
Recalls usually affect specific lots from one maker, not every version of a drug. Class I is the most serious; most drug recalls are Class II. FDA recalls (opens in a new tab)
Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.