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Ondansetron Hcl

Brand names: Ondansetron Hcl

Serotonin-3 Receptor Antagonist Oral

At a glance

Medicare prescriptions, 2024
3,024,371
Medicare drug cost
$53.6M
Average cost per prescription
$17.71
Clinicians who prescribed it
98,722

Where it is prescribed

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List the prescribers in any state, county, city or ZIP code →

What it is used for

1. Indications and Usage Section 1 INDICATIONS AND USAGE Ondansetron tablets are indicated for the prevention of nausea and vomiting associated with: highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m2 initial and repeat courses of moderately emetogenic cancer chemotherapy radiotherapy in patients receiving either total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen Ondansetron tablets

From the FDA-approved prescribing information (label dated March 2026). Full labels on DailyMed (opens in a new tab)

Who prescribes it

All prescribers, by place, name or specialty →

Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.

Trend, 2019–2024

Medicare prescriptions rose 29% from 2019 to 2024.

Medicare Part D prescriptions per year, all prescribers
  • 20193,232,345
  • 20203,295,476
  • 20213,452,761
  • 20223,558,848
  • 20233,907,285
  • 20244,178,737

Biggest change by state since 2019

  • Puerto Rico +147%
  • Minnesota +70%
  • South Dakota +52%
  • Rhode Island +50%
  • Michigan +47%
  • Mississippi (smallest change) +11%
  • Louisiana (smallest change) +12%

From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.

What it looks like

Pills from 3 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.

Advanced Rx of Tennessee, LLC

StrengthLooks likeImprint
8 mgyellow oval tablet, 8 mmF 92

Ax Pharmaceutical Corp

StrengthLooks likeImprint
1 gwhite powder

Bluebay Shandong Co.,ltd

StrengthLooks likeImprint
1 gwhite powder

Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.

Industry payments about this drug

No industry payments to clinicians named this drug in 2025.

Recalls and shortages

Not on the FDA drug shortage list.

2 recalls since 2020

  • Dec 2025 · Glenmark Pharmaceuticals Inc., USA · Class II
    Defective container: Preferred Pharmaceuticals received a letter from the manufacturer Glenmark, that the blister packs are not fully sealed and tablets falling out. Preferred Pharmaceuticals purchased the finished product and repackaged the product for sale.
  • Apr 2022 · McKesson Medical-Surgical Inc. Corporate Office · Class II
    cGMP deviations: Temperature abuse

See all recalls →

Recalls usually affect specific lots from one maker, not every version of a drug. Class I is the most serious; most drug recalls are Class II. FDA recalls (opens in a new tab)

Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.