Ondansetron
Brand names: Ondansetron Odt
At a glance
- Medicare prescriptions, 2024
- 3,464,005
- Medicare drug cost
- $52.0M
- Average cost per prescription
- $15.01
- Clinicians who prescribed it
- 131,360
Where it is prescribed
List the prescribers in any state, county, city or ZIP code →
What it is used for
1. Indications and Usage Section 1 INDICATIONS AND USAGE Ondansetron orally disintegrating tablets are indicated for the prevention of nausea and vomiting associated with: highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m2 initial and repeat courses of moderately emetogenic cancer chemotherapy radiotherapy in patients receiving either total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen Ondansetron orally disintegrating tablets also indicated for the prevention of postoperative nausea and/or vomiting.
From the FDA-approved prescribing information (label dated December 2024). Full labels on DailyMed (opens in a new tab)
Who prescribes it
- Family Medicine 20.8%
- Nurse Practitioners 19.9%
- Emergency Medicine 14.2%
- Internal Medicine 12.7%
- Physician Assistants 11.7%
- Gastroenterology 3.6%
- Hematology & Oncology 3.4%
- Orthopedic Surgery 2.3%
- General Surgery 1.4%
- Medical Oncology 1.2%
- Neurology 0.7%
- Hospitalist 0.6%
All prescribers, by place, name or specialty →
Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.
Trend, 2019–2024
Medicare prescriptions rose 113% from 2019 to 2024.
Biggest change by state since 2019
- Alabama +159%
- Mississippi +153%
- Idaho +148%
- Michigan +146%
- Tennessee +146%
- Hawaii (smallest change) +64%
- Wisconsin (smallest change) +72%
From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.
What it looks like
Pills from 2 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.
Advanced Rx of Tennessee, LLC
| Strength | Looks like | Imprint |
|---|---|---|
| 4 mg | white round tablet, 5 mm | 5 E |
Remedyrepack Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 8 mg | white round tablet, 8 mm | G 8 |
Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.
Industry payments about this drug
No industry payments to clinicians named this drug in 2025.
Recalls and shortages
Not on the FDA drug shortage list.
1 recall since 2020
- Dec 2025 · Glenmark Pharmaceuticals Inc., USA · Class II
Defective container: Preferred Pharmaceuticals received a letter from the manufacturer Glenmark, that the blister packs are not fully sealed and tablets falling out. Preferred Pharmaceuticals purchased the finished product and repackaged the product for sale.
Recalls usually affect specific lots from one maker, not every version of a drug. Class I is the most serious; most drug recalls are Class II. FDA recalls (opens in a new tab)
Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.