Oxycodone Myristate
Brand names: Xtampza Er
Part of: Opioid painkillers
At a glance
- Medicare prescriptions, 2024
- 314,085
- Medicare drug cost
- $197.5M
- Average cost per prescription
- $629
- Clinicians who prescribed it
- 8,010
Where it is prescribed
List the prescribers in any state, county, city or ZIP code →
What it is used for
XTAMPZA ER is indicated for the management of severe and persistent pain that requires an opioid analgesic and that cannot be adequately treated with alternative options, including immediate-release opioids.
From the FDA-approved prescribing information (label dated December 2025). Full labels on DailyMed (opens in a new tab)
Boxed warning
WARNING: SERIOUS AND LIFE-THREATENING RISKS FROM USE OF XTAMPZA ER
The FDA’s strongest warning on a label. It doesn’t mean the drug is unsafe for most people; talk to your doctor or pharmacist before stopping or changing any medicine.
Who prescribes it
- Pain Medicine 29.6%
- Nurse Practitioners 27.7%
- Physician Assistants 14.3%
- Family Medicine 7.3%
- Physical Medicine & Rehabilitation (PM&R) 5.7%
- Internal Medicine 4.9%
- Anesthesiology 3.2%
- Hospice & Palliative Medicine 1.2%
- Neurology 1.2%
- Hematology & Oncology 0.7%
- Sports Medicine 0.5%
- General Practice 0.4%
All prescribers, by place, name or specialty →
Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.
Trend, 2019–2024
Medicare prescriptions rose 49% from 2019 to 2024.
Biggest change by state since 2019
- Pennsylvania +104%
- New York +84%
- New Jersey +75%
- Colorado +67%
- North Carolina +65%
- Missouri (smallest change) +14%
- Virginia (smallest change) +16%
From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.
What it looks like
Pills from 1 maker on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.
Collegium Pharmaceutical, Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 9 mg | white capsule, 16 mm | XTAMPZA ER 9 MG |
| 13.5 mg | white capsule, 18 mm | XTAMPZA ER 13 5 MG |
| 18 mg | white capsule, 19 mm | XTAMPZA ER 18 MG |
| 27 mg | white capsule, 22 mm | XTAMPZA ER 27 MG |
| 36 mg | white capsule, 23 mm | XTAMPZA ER 36 MG |
Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.
Industry payments about this drug
No industry payments to clinicians named this drug in 2025.
Recalls and shortages
Not on the FDA drug shortage list.
No FDA-reported recalls since 2020.
Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.