Risperidone
Brand names: Risperdal, Risperidone, Risperidone Odt, Perseris, Uzedy
Part of: Antipsychotics
At a glance
- Medicare prescriptions, 2024
- 3,271,260
- Medicare drug cost
- $115.6M
- Average cost per prescription
- $35.34
- Clinicians who prescribed it
- 61,772
Where it is prescribed
List the prescribers in any state, county, city or ZIP code →
What it is used for
Risperidone is an atypical antipsychotic agent indicated for: Treatment of schizophrenia As monotherapy or adjunctive therapy with lithium or valproate, for the treatment of acute manic or mixed episodes associated with Bipolar I Disorder Treatment of irritability associated with autistic disorder
From the FDA-approved prescribing information (label dated August 2026). Full labels on DailyMed (opens in a new tab)
Boxed warning
WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Risperidone is not approved for the treatment of patients with dementia-related psychosis.
The FDA’s strongest warning on a label. It doesn’t mean the drug is unsafe for most people; talk to your doctor or pharmacist before stopping or changing any medicine.
Who prescribes it
- Psychiatry 28.7%
- Psychiatric Nurse Practitioners 22.3%
- Nurse Practitioners 12.6%
- Internal Medicine 11.9%
- Family Medicine 11.4%
- Physician Assistants 4.1%
- Geriatric Medicine 2.3%
- Child & Adolescent Psychiatry 1.7%
- General Practice 1.4%
- Neurology 1.3%
- Hospitalist 0.5%
- Addiction Medicine 0.2%
All prescribers, by place, name or specialty →
Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.
Trend, 2019–2024
Medicare prescriptions fell 11% from 2019 to 2024.
Biggest change by state since 2019
- Montana +5%
- New Hampshire +4%
- Puerto Rico −0%
- Arizona −0%
- Idaho −1%
- North Dakota (smallest change) −25%
- Georgia (smallest change) −22%
From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.
What it looks like
Pills from 3 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.
A-S Medication Solutions
| Strength | Looks like | Imprint |
|---|---|---|
| 0.25 mg | orange round tablet, 5 mm | RI1 |
| 0.5 mg | orange round tablet, 7 mm | RI2 |
| 1 mg | white round tablet, 8 mm | RI3 |
| 2 mg | yellow round tablet, 8 mm | RI4 |
Atlantic Biologicals Corp.
| Strength | Looks like | Imprint |
|---|---|---|
| 1 mg | white solution | |
Janssen Pharmaceuticals, Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 0.5 mg | brown oval tablet, 9 mm | RIS 0 5 JANSSEN |
| 0.5 mg | orange round tablet, 10 mm | R0 5 |
| 1 mg | white oval tablet, 12 mm | R1 JANSSEN |
| 1 mg | orange square tablet, 11 mm | R1 |
| 2 mg | orange oval tablet, 12 mm | R2 JANSSEN |
| 2 mg | orange square tablet, 11 mm | R2 |
| 3 mg | yellow oval tablet, 14 mm | R3 JANSSEN |
| 3 mg | orange round tablet, 14 mm | R3 |
| 4 mg | green oval tablet, 15 mm | R4 JANSSEN |
| 4 mg | orange round tablet, 16 mm | R4 |
Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.
Industry payments about this drug
Drug makers reported $5.7M in payments to clinicians that named this drug in 2025 (meals, speaking, consulting and similar).
- Teva Pharmaceuticals USA, Inc. $5.7M
- Janssen Pharmaceuticals, Inc $2,830
Source: CMS Open Payments, general payments (not research), program year 2025. A payment is not evidence of wrongdoing. Payments by doctor
Recalls and shortages
Not on the FDA drug shortage list.
No FDA-reported recalls since 2020.
Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.