Sertraline Hcl
Brand names: Sertraline Hcl, Zoloft
Part of: Antidepressants
At a glance
- Medicare prescriptions, 2024
- 15,223,225
- Medicare drug cost
- $141.7M
- Average cost per prescription
- $9.31
- Clinicians who prescribed it
- 234,564
Where it is prescribed
List the prescribers in any state, county, city or ZIP code →
What it is used for
Sertraline hydrochloride tablets are indicated for the treatment of the following: Major depressive disorder (MDD) Obsessive-compulsive disorder (OCD) Panic disorder (PD) Posttraumatic stress disorder (PTSD) Social anxiety disorder (SAD) Premenstrual dysphoric disorder (PMDD)
From the FDA-approved prescribing information (label dated May 2024). Full labels on DailyMed (opens in a new tab)
Boxed warning
WARNING: SUICIDAL THOUGHTS AND BEHAVIORS Antidepressants increased the risk of suicidal thoughts and behavior in pediatric and young adult patients in short-term studies. Closely monitor all antidepressant-treated patients for clinical worsening, and for emergence of suicidal thoughts and behaviors.
The FDA’s strongest warning on a label. It doesn’t mean the drug is unsafe for most people; talk to your doctor or pharmacist before stopping or changing any medicine.
Who prescribes it
- Family Medicine 28.9%
- Internal Medicine 22.3%
- Nurse Practitioners 18.3%
- Psychiatry 9.0%
- Psychiatric Nurse Practitioners 7.6%
- Physician Assistants 5.7%
- Geriatric Medicine 2.1%
- General Practice 1.4%
- Neurology 1.4%
- Hospitalist 0.5%
- Child & Adolescent Psychiatry 0.5%
- Cardiology 0.2%
All prescribers, by place, name or specialty →
Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.
Trend, 2019–2024
Medicare prescriptions rose 16% from 2019 to 2024.
Biggest change by state since 2019
- Indiana +36%
- Florida +28%
- New Hampshire +26%
- Connecticut +24%
- Alabama +24%
- North Dakota (smallest change) −1%
- Rhode Island (smallest change) +0%
From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.
What it looks like
Pills from 5 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.
Almatica Pharma LLC
| Strength | Looks like | Imprint |
|---|---|---|
| 150 mg | white capsule, 18 mm | ALM 664 |
| 200 mg | white capsule, 19 mm | ALM 672 |
Biocon Pharma Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 150 mg | white capsule, 2 mm | |
| 200 mg | yellow capsule, 1 mm | |
Direct_rx
| Strength | Looks like | Imprint |
|---|---|---|
| 50 mg | blue capsule, 10 mm, scored to split in 2 | A 1 7 |
Umedica Laboratories USA Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 150 mg | white capsule, 2 mm | |
| 200 mg | yellow capsule, 1 mm | |
Viatris Specialty LLC
| Strength | Looks like | Imprint |
|---|---|---|
| 25 mg | green oval tablet, 8 mm, scored to split in 2 | ZOLOFT 25 MG |
| 50 mg | blue oval tablet, 10 mm, scored to split in 2 | ZOLOFT 50 MG |
| 100 mg | yellow oval tablet, 13 mm, scored to split in 2 | ZOLOFT 100 MG |
Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.
Industry payments about this drug
No industry payments to clinicians named this drug in 2025.
Recalls and shortages
Not on the FDA drug shortage list.
2 recalls since 2020
- Nov 2025 · Lupin Pharmaceuticals Inc. · Class II
Defective container - seal not adhering to bottles - Dec 2023 · Legacy Pharmaceutical PAckaging LLC · Class II
CGMP Deviations: Inadequate line clearance which may result in a potential comingling of product.
Recalls usually affect specific lots from one maker, not every version of a drug. Class I is the most serious; most drug recalls are Class II. FDA recalls (opens in a new tab)
Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.