Sodium Zirconium Cyclosilicate
Brand names: Lokelma
At a glance
- Medicare prescriptions, 2024
- 218,763
- Medicare drug cost
- $160.2M
- Average cost per prescription
- $732
- Clinicians who prescribed it
- 8,059
Where it is prescribed
List the prescribers in any state, county, city or ZIP code →
What it is used for
LOKELMA is indicated for the treatment of hyperkalemia in adults. Limitation of Use LOKELMA should not be used as an emergency treatment for life-threatening hyperkalemia because of its delayed onset of action.
From the FDA-approved prescribing information (label dated March 2026). Full labels on DailyMed (opens in a new tab)
Who prescribes it
- Nephrology (Kidney) 57.3%
- Nurse Practitioners 15.0%
- Internal Medicine 13.9%
- Family Medicine 5.4%
- Physician Assistants 2.5%
- Geriatric Medicine 1.7%
- Hospitalist 0.7%
- Cardiology 0.6%
- General Practice 0.6%
- Pulmonology 0.3%
- Transplant Surgery 0.3%
- Gastroenterology 0.2%
All prescribers, by place, name or specialty →
Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.
Trend, 2019–2024
Medicare prescriptions rose 2,844% from 2019 to 2024.
From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.
Industry payments about this drug
Drug makers reported $731,043 in payments to clinicians that named this drug in 2025 (meals, speaking, consulting and similar).
- AstraZeneca Pharmaceuticals LP $719,935
- AstraZeneca UK Limited $6,909
- AstraZeneca Ab $4,199
Source: CMS Open Payments, general payments (not research), program year 2025. A payment is not evidence of wrongdoing. Payments by doctor
Recalls and shortages
Not on the FDA drug shortage list.
No FDA-reported recalls since 2020.
Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.