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Theophylline Anhydrous

Brand names: Theo-24, Theophylline, Theophylline Er

Methylxanthine Oral

At a glance

Medicare prescriptions, 2024
91,961
Medicare drug cost
$7.5M
Average cost per prescription
$81.64
Clinicians who prescribed it
3,573

Where it is prescribed

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List the prescribers in any state, county, city or ZIP code →

What it is used for

Theophylline is indicated for the treatment of the symptoms and reversible airflow obstruction associated with chronic asthma and other chronic lung diseases, e.g., emphysema and chronic bronchitis.

From the FDA-approved prescribing information (label dated December 2025). Full labels on DailyMed (opens in a new tab)

Who prescribes it

All prescribers, by place, name or specialty →

Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.

Trend, 2019–2024

Medicare prescriptions fell 47% from 2019 to 2024.

Medicare Part D prescriptions per year, all prescribers
  • 2019331,702
  • 2020291,531
  • 2021252,835
  • 2022222,128
  • 2023194,551
  • 2024176,223

Biggest change by state since 2019

  • Indiana −27%
  • Puerto Rico −30%
  • Mississippi −34%
  • Florida −40%
  • Louisiana −40%
  • Iowa (smallest change) −57%
  • Illinois (smallest change) −56%

From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.

What it looks like

Pills from 5 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.

Endo USA, Inc.

StrengthLooks likeImprint
100 mgorange capsule, 16 mmTHEO 24 100 MG AP 2832
200 mgorange capsule, 19 mmTHEO 24 200 MG AP 2842
300 mgorange capsule, 22 mmTHEO 24 300 MG AP 2852
400 mgpink capsule, 22 mmTHEO 24 400 MG AP 2902

Golden State Medical Supply, Inc.

StrengthLooks likeImprint
400 mgwhite round tablet, 11 mm, scored to split in 2N T4
600 mgwhite oval tablet, 19 mm, scored to split in 2NT6

Nostrum Laboratories, Inc.

StrengthLooks likeImprint
400 mgwhite round tablet, 11 mm, scored to split in 2N T4
600 mgwhite oval tablet, 19 mm, scored to split in 2NT6

Proficient Rx LP

StrengthLooks likeImprint
400 mgwhite round tablet, 11 mm, scored to split in 2N T4
600 mgwhite oval tablet, 19 mm, scored to split in 2NT6

Westminster Pharmaceuticals, LLC

StrengthLooks likeImprint
400 mgwhite round tablet, 11 mm, scored to split in 2N T4
600 mgwhite oval tablet, 19 mm, scored to split in 2NT6

Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.

Industry payments about this drug

No industry payments to clinicians named this drug in 2025.

Recalls and shortages

Not on the FDA drug shortage list.

3 recalls since 2020

  • Aug 2025 · Glenmark Pharmaceuticals Inc., USA · Class II
    Failed Dissolution Specifications: Failure results (above) were reported for the Dissolution (by UV) test for commercial annual stability at the long-term shelf life stability interval, wherein the dissolution results do not comply with L3 stage dissolution criteria.
  • May 2025 · Glenmark Pharmaceuticals Inc., USA · Class II
    OOS results reported for the Dissolution (by UV) test.
  • Mar 2021 · Cardinal Health Inc. · Class II
    CGMP Deviations: Intermittent exposure to temperature excursion during storage.

See all recalls →

Recalls usually affect specific lots from one maker, not every version of a drug. Class I is the most serious; most drug recalls are Class II. FDA recalls (opens in a new tab)

Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.