Trazodone Hcl
Brand names: Trazodone Hcl
Part of: Antidepressants
At a glance
- Medicare prescriptions, 2024
- 17,432,328
- Medicare drug cost
- $157.6M
- Average cost per prescription
- $9.04
- Clinicians who prescribed it
- 252,467
Where it is prescribed
List the prescribers in any state, county, city or ZIP code →
What it is used for
1. Indications and Usage Trazodone hydrochloride tablets are indicated for the treatment of major depressive disorder (MDD) in adults.
From the FDA-approved prescribing information (label dated December 2024). Full labels on DailyMed (opens in a new tab)
Boxed warning
WARNING: SUICIDAL THOUGHTS AND BEHAVIORS Antidepressants increased the risk of suicidal thoughts and behaviors in pediatric and young adult patients in short-term studies. Closely monitor all antidepressant-treated patients for clinical worsening, and for emergence of suicidal thoughts and behaviors. Trazodone is not approved for use in pediatric patients.
The FDA’s strongest warning on a label. It doesn’t mean the drug is unsafe for most people; talk to your doctor or pharmacist before stopping or changing any medicine.
Who prescribes it
- Family Medicine 27.2%
- Internal Medicine 21.1%
- Nurse Practitioners 17.6%
- Psychiatry 10.9%
- Psychiatric Nurse Practitioners 9.2%
- Physician Assistants 5.8%
- Geriatric Medicine 1.8%
- General Practice 1.2%
- Neurology 1.1%
- Child & Adolescent Psychiatry 0.5%
- Hospitalist 0.4%
- Pain Medicine 0.3%
All prescribers, by place, name or specialty →
Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.
Trend, 2019–2024
Medicare prescriptions rose 31% from 2019 to 2024.
Biggest change by state since 2019
- Puerto Rico +53%
- Florida +47%
- Nebraska +44%
- Illinois +41%
- Utah +40%
- Rhode Island (smallest change) +7%
- Massachusetts (smallest change) +19%
From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.
What it looks like
Pills from 4 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.
Advanced Rx Pharmacy of Tennessee, LLC
| Strength | Looks like | Imprint |
|---|---|---|
| 50 mg | white round tablet, 8 mm, scored to split in 2 | 8 05 |
Ax Pharmaceutical Corp
| Strength | Looks like | Imprint |
|---|---|---|
| 1 g | white powder | |
Bluebay Shandong Co.,ltd
| Strength | Looks like | Imprint |
|---|---|---|
| 1 g | white powder | |
Direct_rx
| Strength | Looks like | Imprint |
|---|---|---|
| 50 mg | white round tablet, 8 mm, scored to split in 2 | 05 |
Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.
Industry payments about this drug
No industry payments to clinicians named this drug in 2025.
Recalls and shortages
Not on the FDA drug shortage list.
3 recalls since 2020
- Aug 2026 · Teva Pharmaceuticals USA, Inc · Class II
Presence of Foreign Tablets/Capsules - Jan 2026 · Granules Pharmaceuticals Inc. · Class II
Presence of Foreign Tablets/Capsules - Dec 2025 · Zydus Pharmaceuticals (USA) Inc · Class III
Failed Tablet/Capsule Specifications: Product complaint received that some tablets had a dent on the plain side of the tablet surface.
Recalls usually affect specific lots from one maker, not every version of a drug. Class I is the most serious; most drug recalls are Class II. FDA recalls (opens in a new tab)
Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.