Trimethoprim
Brand names: Trimethoprim
At a glance
- Medicare prescriptions, 2024
- 121,225
- Medicare drug cost
- $6.2M
- Average cost per prescription
- $51.08
- Clinicians who prescribed it
- 4,391
Where it is prescribed
List the prescribers in any state, county, city or ZIP code →
What it is used for
To reduce the development of drug-resistant bacteria and maintain the effectiveness of trimethoprim tablets, USP and other antibacterial drugs, trimethoprim tablets, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. For the treatment of initial episodes of uncomplicated urinary tract infections due to susceptible strains of the following organisms: Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Enterobacter species, and coagulase-negative Staphylococcus species, including S. saprophyticus. Cultures and susceptibility tests should be performed to determine the susceptibility of the bacteria to trimethoprim. Therapy may be initiated prior to obtaining the results of these tests.
From the FDA-approved prescribing information (label dated June 2024). Full labels on DailyMed (opens in a new tab)
Who prescribes it
- Urology 34.8%
- Nurse Practitioners 20.7%
- Family Medicine 12.6%
- Physician Assistants 11.7%
- Internal Medicine 9.4%
- Urogynecology 5.4%
- Geriatric Medicine 1.5%
- OB-GYN (Obstetrics & Gynecology) 1.3%
- Infectious Disease 0.7%
- Nephrology (Kidney) 0.3%
- Hospitalist 0.3%
- General Practice 0.2%
All prescribers, by place, name or specialty →
Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.
Trend, 2019–2024
Medicare prescriptions fell 27% from 2019 to 2024.
Biggest change by state since 2019
- Illinois −16%
- Florida −17%
- Wisconsin −18%
- Alabama −20%
- North Carolina −20%
- Iowa (smallest change) −39%
- Pennsylvania (smallest change) −38%
From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.
What it looks like
Pills from 4 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.
Lupin Pharmaceuticals,inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 100 mg | white round tablet, 10 mm, scored to split in 2 | NL 330 |
Pd-Rx Pharmaceuticals, Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 800 mg / 160 mg trimethoprim | white oval tablet, 19 mm, scored to split in 2 | H 49 |
Redpharm Drug
| Strength | Looks like | Imprint |
|---|---|---|
| 800 mg / 160 mg trimethoprim | white oval tablet, 19 mm, scored to split in 2 | IP 272 |
Remedyrepack Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 10000 [iU] / 1 mg trimethoprim | yellow solution/ drops | |
Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.
Industry payments about this drug
No industry payments to clinicians named this drug in 2025.
Recalls and shortages
Not on the FDA drug shortage list.
No FDA-reported recalls since 2020.
Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.