Zolpidem Tartrate
Brand names: Ambien, Ambien Cr, Zolpidem Tartrate, Edluar, Zolpidem Tartrate Er
At a glance
- Medicare prescriptions, 2024
- 7,094,127
- Medicare drug cost
- $56.0M
- Average cost per prescription
- $7.90
- Clinicians who prescribed it
- 150,057
Where it is prescribed
List the prescribers in any state, county, city or ZIP code →
What it is used for
Zolpidem tartrate tablets, USP a gamma-amino butyric acid (GABA) A receptor positive modulator, is indicated for the short-term treatment of insomnia characterized by difficulties with sleep initiation.
From the FDA-approved prescribing information (label dated August 2026). Full labels on DailyMed (opens in a new tab)
Boxed warning
WARNING: COMPLEX SLEEP BEHAVIORS Complex sleep behaviors including sleep-walking, sleep-driving, and engaging in other activities while not fully awake may occur following use of zolpidem tartrate tablets. Some of these events may result in serious injuries, including death. Discontinue zolpidem tartrate tablets immediately if a patient experiences a complex sleep behavior. WARNING: COMPLEX SLEEP BEHAVIORS See full prescribing information for complete boxed warning. Complex sleep behaviors including sleep-walking, sleep-driving, and engaging in other activities while not fully awake may occur following use of zolpidem tartrate tablets. Some of these events may result in serious injuries, including death. Discontinue zolpidem tartrate tablets immediately if a patient experiences a complex sleep behavior.
The FDA’s strongest warning on a label. It doesn’t mean the drug is unsafe for most people; talk to your doctor or pharmacist before stopping or changing any medicine.
Who prescribes it
- Family Medicine 32.6%
- Internal Medicine 27.2%
- Nurse Practitioners 12.9%
- Psychiatry 8.4%
- Physician Assistants 5.5%
- Psychiatric Nurse Practitioners 4.0%
- General Practice 1.2%
- Neurology 0.9%
- Pulmonology 0.9%
- Geriatric Medicine 0.7%
- Pain Medicine 0.7%
- Cardiology 0.6%
All prescribers, by place, name or specialty →
Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.
Trend, 2019–2024
Medicare prescriptions rose 5% from 2019 to 2024.
Biggest change by state since 2019
- Puerto Rico +27%
- Utah +19%
- Alabama +17%
- Florida +15%
- Kentucky +15%
- Alaska (smallest change) −11%
- Missouri (smallest change) −6%
From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.
What it looks like
Pills from 4 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.
Pd-Rx Pharmaceuticals, Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 5 mg | white round tablet, 5 mm | E 78 |
Preferred Pharmaceuticals Inc.
| Strength | Looks like | Imprint |
|---|---|---|
| 6.25 mg | pink round tablet, 8 mm | LU E61 |
Torrent Pharmaceuticals Limited
| Strength | Looks like | Imprint |
|---|---|---|
| 5 mg | red oval tablet, 10 mm | 5 MG |
| 10 mg | yellow oval tablet, 10 mm | 10 MG |
Torrent Pharmaceuticals Limited
| Strength | Looks like | Imprint |
|---|---|---|
| 7.5 mg | white capsule, 16 mm | U4 7 5 |
Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.
Industry payments about this drug
No industry payments to clinicians named this drug in 2025.
Recalls and shortages
Not on the FDA drug shortage list.
1 recall since 2020
- Jan 2024 · Sun Pharmaceutical Industries Inc · Class II
CGMP Deviations: Microbial contamination was reported in stagnant water in the duct of the manufacturing equipment.
Recalls usually affect specific lots from one maker, not every version of a drug. Class I is the most serious; most drug recalls are Class II. FDA recalls (opens in a new tab)
Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.