LOWER: Lomitapide Observational Worldwide Evaluation Registry
Completed · NCT02135705
Conditions: Homozygous Familial Hypercholesterolemia
At a glance
- Research payments reported, 2025
- $25,902
- U.S. investigators named
- 16
- Sites paid
- 16
- Planned or actual enrollment
- 260
About the trial
- Sponsor
- Amryt Pharma
- Tested
- Lomitapide (drug)
- Dates
- Started 2014-03-18; completion 2026-04-27
- Results posted
- Not yet
This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and effectiveness of lomitapide.
From ClinicalTrials.gov, last updated 2026-05-12. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Chiesi USA, Inc. reported $25,902 in research payments for this study in 2025 (43 payments).
Products named: Juxtapid
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Kenneth J. Bescak, MD Cardiology · Cottonwood, AZ
- Joseph L. Lillo, DO, FNLA, FAPCR Family Medicine · Scottsdale, AZ
- Sanjiv G. Faldu, M.D. Cardiology · Red Bluff, CA
- Paul E. Ziajka, MD, PHD Specialist · Winter Park, FL
- Janice Mcalister, NP Nurse Practitioners · Atlanta, GA
- David H. Song, MD FACE Interventional Cardiology · Tucker, GA
- James A. Trippi, MD Cardiology · Indianapolis, IN
- Peter S. Fail, MD Heart Failure & Transplant Cardiology · Houma, LA
- Thomas Knickelbine, MD Cardiology · Minneapolis, MN
- Dharmesh S. Patel, MD Cardiology · Southaven, MS
- John A. Pasquini, MD Interventional Cardiology · Charlotte, NC
- John S. Henry, MD Cardiology · Omaha, NE
- James A. Underberg, MD Internal Medicine · New York, NY
- Gerald E. Pytlewski, D.O. Cardiology · Bethlehem, PA
- Susan Washburn, CRNP Nurse Practitioners · Allentown, PA
- Joshua D. Liberman, M.D. Cardiology · Mequon, WI
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- $8,200
- Central Indiana Health System Cardiac Services Inc $4,940
- Piedmont Heart Institute Inc $2,902
- Wcg Irb $2,720
- Cardiovascular Institute of the South Clinical Res $1,711
- Novant Health Huntersville Medical Center, NC $1,500
- Jau LLC $1,493
- Physicians Clinic Inc DBA Methodist Physicians Cli $616
- Stern Cardiovascular Foundation Inc $380
- Atlanta Heart Specialists LLC $300
- Verde Valley Medical Center, AZ $300
- The Heart Care Group PC $250
- Minneapolis Heart Institute Foundation $150
- St Lukes Health Network Inc DBA St Lukes Universit $125
- Ascension Columbia St Marys Hospital Milwaukee, WI $120
- The Florida Lipid Institute PA $100
- Elite Clinical Studies LLC $95
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.