A Study of TAK-788 in Adults With Non-Small Cell Lung Cancer
Completed · Phase 1, Phase 2 · NCT02716116
Conditions: Carcinoma, Non-Small-Cell Lung
At a glance
- Research payments reported, 2025
- $20,002
- U.S. investigators named
- 4
- Sites paid
- 4
- Planned or actual enrollment
- 324
About the trial
- Sponsor
- Takeda
- Tested
- TAK-788 (drug)
- Dates
- Started 2016-06-16; completion 2026-09-29
- Results posted
- Not yet
This study is about a medicine called TAK-788, also known as mobocertinib, given to adults with non-small cell lung cancer. The main aims of this study are to check if there are any side effects from TAK-788, to learn how TAK-788 is processed by the body, and to determine the best dose of TAK-788 to treat this condition. Participants will take TAK-788 capsules with chemotherapy. Participants will continue to take TAK-788 unless they or their doctor decide they should stop this treatment. Participants will take TAK-788 capsules with or without chemotherapy under antidiarrhea prevention to determine the safety of TAK-788 treatment. Non-Asian, non-White participants will take TAK-788 to dete…
From ClinicalTrials.gov, last updated 2026-10-28. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Takeda Pharmaceuticals U.S.A., Inc. reported $20,002 in research payments for this study in 2025 (6 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Sai-hong I Ou, MD Hematology & Oncology · Orange, CA
- Tarek M. Mekhail, M.D. Hematology & Oncology · Orlando, FL
- Rendon C. Nelson, M.D. Radiology · Durham, NC
- Alexander I. Spira, M.D. Medical Oncology · Fairfax, VA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Uci Health-Orange, CA $18,593
- Virginia Cancer Specialists PC $796
- Radmd LLC $540
- Adventhealth Orlando, FL $73
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.