Humacyte Acellular Tissue Engineered Vessel (ATEV) in Patients With Vascular Trauma
Completed · Phase 2, Phase 3 · NCT03005418
Conditions: Trauma, Vascular System Injury
At a glance
- Research payments reported, 2025
- $111,631
- U.S. investigators named
- 12
- Sites paid
- 12
- Planned or actual enrollment
- 72
About the trial
- Sponsor
- Humacyte, Inc. (with Atlantic Research Group, U.S. Army Medical Research and Development Command)
- Tested
- Acellular Tissue Engineered Vessel (ATEV) (biological)
- Dates
- Started 2018-09-01; completion 2026-05-15
- Results posted
- Yes
This study evaluates the use of the Acellular Tissue Engineered Vessel (ATEV) in adults with vascular trauma below the neck who are undergoing vascular reconstructive surgery. There will be an extremity cohort and an torso cohort. All subjects will be implanted with an ATEV as an interposition vessel or bypass using standard vascular surgical techniques. There is no control arm.
From ClinicalTrials.gov, last updated 2026-07-29. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Humacyte Global, Inc. reported $111,631 in research payments for this study in 2025 (16 payments).
Products named: Symvess
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Roy M. Fujitani, M.D. Vascular Surgery · Orange, CA
- Ernest E. Moore, MD General Surgery · Denver, CO
- Aurelia F. Thibonnier, MD Vascular Surgery · Wesley Chapel, FL
- Ravi Rajani, M.D. General Surgery · Atlanta, GA
- Ying Wei Lum, M.D. Vascular Surgery · Baltimore, MD
- Carl Freeman, MD General Surgery · Saint Louis, MO
- David J. Skarupa, M.D. General Surgery · Greenville, NC
- Kevin W. Southerland, MD Student in an Organized Health Care Education/Training Program · Durham, NC
- Philip M. Batista, M.D. Vascular Surgery · Camden, NJ
- Michael A. Curi, MD Vascular Surgery · Newark, NJ
- Gregory A. Magee, M.D. Vascular Surgery · New York, NY
- Lawrence B. Oresanya, M.D Vascular Surgery · Philadelphia, PA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Denver Health & Hospital Authority, CO $22,275
- John Hopkins University $20,675
- Uci Health-Orange, CA $17,463
- Temple University-Of the Commonwealth System of Higher Education. $13,150
- University of South Florida $9,416
- Rutgers, the State University of New Jersey $7,410
- St. Louis University $6,730
- University of Southern California $4,650
- Duke University $3,076
- University of Florida $3,000
- Emory University Office for Clinical Research $2,788
- Cooper University Hospital, NJ $1,000
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.