Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial
Active, not recruiting · Not applicable · NCT03108456
Conditions: Coronary Artery Disease, Ischemic Heart Disease, Non ST Segment Elevation Myocardial Infarction
At a glance
- Research payments reported, 2025
- $954,002
- U.S. investigators named
- 66
- Sites paid
- 64
- Planned or actual enrollment
- 2,005
About the trial
- Sponsor
- Abbott Medical Devices (with Cardiovascular Research Foundation, New York)
- Tested
- Orbital Atherectomy (device), Balloon (device)
- Dates
- Started 2017-03-27; completion 2025-06-12
- Results posted
- Not yet
This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions prior to implantation of drug-eluting stents (DES).
From ClinicalTrials.gov, last updated 2023-10-06. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Abbott Laboratories reported $954,002 in research payments for this study in 2025 (154 payments).
Products named: Diamondback Coronary
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Ayman Jamal, MD Cardiology · Phoenix, AZ
- Georges Y. Nseir, MD Interventional Cardiology · Chandler, AZ
- Suhail Y. Dohad, M.D. Interventional Cardiology · Beverly Hills, CA
- Ehtisham Mahmud, M.D. Interventional Cardiology · San Diego, CA
- Kendrick Shunk, M.D. Interventional Cardiology · San Francisco, CA
- John D. Altman, MD Cardiology · Lakewood, CO
- Michael W. Cleman, MD Cardiology · Branford, CT
- Steven Pfau, MD Cardiology · New Haven, CT
- Ron Waksman, M.D. Interventional Cardiology · Washington, DC
- Olcay Aksoy, M.D. Interventional Cardiology · Miami Beach, FL
- Dominick J. Angiolillo, MD Interventional Cardiology · Jacksonville, FL
- Rohit Bhatheja, MD Cardiology · Orlando, FL
- Robert L. Feldman, M.D. Interventional Cardiology · Ocala, FL
- Arthur C. Lee, MD Interventional Cardiology · Gainesville, FL
- Thomas E. Noel, M.D. Cardiology · Tallahassee, FL
- Juan Pastor-cervantes, MD Interventional Cardiology · Hollywood, FL
- Saihari Sadanandan, M.D. Interventional Cardiology · Tampa, FL
- Alok Singh, MD Interventional Cardiology · Tampa, FL
- Nima Ghasemzadeh, MD Interventional Cardiology · Braselton, GA
- Kishore J. Harjai, MD Interventional Cardiology · Macon, GA
- Prashant Kaul, M.D. Interventional Cardiology · Atlanta, GA
- Gautam Kumar, MBBS, MRCPUK Interventional Cardiology · Atlanta, GA
- Bruce E. Lewis, MD Interventional Cardiology · Maywood, IL
- Adhir R. Shroff, M.D. Cardiology · Chicago, IL
- Jithendra P. Choudary, M.D. Interventional Cardiology · Richmond, IN
- Naresh K. Solankhi, MD Interventional Cardiology · Louisville, KY
- Tarek A. Helmy, MD Interventional Cardiology · Shreveport, LA
- James S. Jenkins, MD Interventional Cardiology · New Orleans, LA
- Brian A. Bergmark, MD Cardiology · Boston, MA
- Gautam Gadey, M.D. Interventional Cardiology · Burlington, MA
- Nikolaos Kakouros, BSC, MBBS, MRCP, PHD Interventional Cardiology · Worcester, MA
- Sergio Waxman, M.D. Interventional Cardiology · Burlington, MA
- Khaldoon Alaswad, MD Interventional Cardiology · Detroit, MI
- Paul M. Grossman, MD Interventional Cardiology · Ann Arbor, MI
- Ivan J. Chavez, MD Interventional Cardiology · Minneapolis, MN
- Daniel D. Dulas, M.D. Interventional Cardiology · Minneapolis, MN
- Wilson L. Ginete Interventional Cardiology · Duluth, MN
- Brian M. Stegman, MD Interventional Cardiology · St Cloud, MN
- Ammar Nasir, MD Interventional Cardiology · Lake St Louis, MO
- Jasvindar Singh, MD Interventional Cardiology · Saint Louis, MO
- Robert G. Wilkins, MD Interventional Cardiology · Hattiesburg, MS
- Steven J. Filby, M.D. Interventional Cardiology · Pinehurst, NC
- William S. Jones, M.D. Interventional Cardiology · Durham, NC
- Joseph S. Rossi, MD Interventional Cardiology · Sanford, NC
- Rajesh V. Swaminathan, M.D. Interventional Cardiology · Durham, NC
- Jordan G. Safirstein, MD Cardiology · Mountain Lakes, NJ
- Vincent Varghese, D.O. Cardiology · Marlton, NJ
- Michael B. Collins, M.D. Interventional Cardiology · New York, NY
- Michael C. Kim, M.D Interventional Cardiology · Manhasset, NY
- Mark A. Menegus, MD Cardiology · Bronx, NY
- Claudia C. Serrano-gomez, M.D. Interventional Cardiology · New York, NY
- Richard A. Shlofmitz, M.D. Interventional Cardiology · Roslyn, NY
- Anil Verma, MD Cardiology · Cincinnati, OH
- Nicholas N. Hanna, M.D. Cardiology · Tulsa, OK
- Daniel P. Sherbet, MD Cardiology · Oklahoma City, OK
- Sahil S. Banka, M.D. Interventional Cardiology · Philadelphia, PA
- Craig A. Frankil, DO Interventional Cardiology · Philadelphia, PA
- David M. Lasorda, DO Interventional Cardiology · Pittsburgh, PA
- Jinnette D. Abbott, MD Interventional Cardiology · Providence, RI
- Brian K. Jefferson, MD Interventional Cardiology · Nashville, TN
- Rahul Sakhuja, MD Interventional Cardiology · Kingsport, TN
- Apurva O. Badheka, M.D. Interventional Cardiology · Denison, TX
- Subhash Banerjee, MD Cardiology · Dallas, TX
- Alpesh R. Shah, M.D. Interventional Cardiology · Pearland, TX
- Deepak R. Talreja, MD Interventional Cardiology · Virginia Beach, VA
- Suhail Q. Allaqaband, MD Interventional Cardiology · Milwaukee, WI
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Northern California Institute for Reseach & Ed $93,366
- Ronald Reagan UCLA Medical Center, CA $89,808
- Trustees of Columbia University $69,592
- Institute for Medical Research Inc. $55,763
- Northeast Georgia Medical Center, Inc, GA $48,343
- Loyola University Chicago $39,040
- Regents of the University of California $34,133
- Lahey Hospital & Medical Center, Burlington, MA $31,454
- University of Michigan Health System, MI $28,002
- Piedmont Heart Institute Inc. $27,415
- Cedars-Sinai Medical Center, CA $27,353
- St. Francis Research & Educational Corp $25,556
- University of Florida $24,546
- Feinstein Institute for Medical Research $23,600
- Minneapolis Heart Institute Foundation $23,018
- Methodist Hospital Research Institute $22,094
- Sentara Norfolk General Hospital, VA $20,722
- St. Louis University $20,285
- Bon Secours Mercy Heatlh Inc $15,970
- Deborah Heart and Lung Center, NJ $15,292
- Brigham and Women's Hospital, MA $13,137
- Foundation for Atlanta Veterans Ed & Research $10,506
- University of Massachusetts $9,600
- Metropolitan Cardiology Consultants $9,512
- Ochsner Medical Center Acute, LA $9,413
- Massachusetts General Hospital, MA $9,315
- St. John Health System $9,213
- Sarah Cannon Research Institute LLC $9,038
- St Josephs Hospital, FL $8,567
- Biomedical Research Alliance of New York LLC $8,320
- Essentia Institute of Rural Health $8,269
- Medstar Health Research Institute $8,234
- Providence Regional Medical Center Everett, WA $8,032
- New York University School of Medicine $7,985
- Centracare - St. Cloud Hospital, MN $7,108
- Adventhealth Orlando, FL $6,787
- University of Illinois Hospital and Clinics, IL $6,399
- Chandler Regional Medical Center, AZ $5,906
- Newark Beth Israel Medical Center, NJ $5,525
- Cardiovascular Research of North Florida LLC $5,265
- Rhode Island Hospital, RI $5,100
- Vascular Heart & Lung Associates $5,000
- Veterans Research & Education Foundation $4,800
- Reid Physician Associates Inc. $3,830
- Uofl Health - Jewish Hospital and Mary & Elizabeth Hospital, KY $3,801
- Duke University Hospital $3,320
- Washington University $3,293
- Allegheny Singer Research Institute $2,798
- Aurora Research Institute LLC $2,689
- Hattiesburg Clinic PA $2,131
- Morristown Medical Center, NJ $2,000
- Hospital of Univ of Pennsylvania, PA $2,000
- Memorial Regional Hospital, FL $1,972
- Colorado Heart & Vascular PC $1,473
- Arkansas Site Management Services LLC $1,321
- Uh Cleveland Medical Center, OH $1,000
- University of North Carolina at Chapel Hill $975
- Dallas VA Research Corporation $928
- Albert Einstein Healthcare Network $862
- Yale University - Treasury Operations $835
- Henry Ford Health Hospital, MI $793
- Advocate Aurora Research Institute LLC $729
- Adventhealth Tampa, FL $681
- Tallahassee Research Institute Inc. $188
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.