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SC-004 Alone or With ABBV-181 in Subjects With Epithelial Ovarian, Fallopian Tube, Primary Peritoneal and Endometrial Cancers

Terminated · Phase 1 · NCT03138408

Conditions: Cancer

At a glance

Research payments reported, 2025
$5,457
U.S. investigators named
1
Sites paid
1
Planned or actual enrollment
24

About the trial

Sponsor
AbbVie
Tested
SC-004 (drug), ABBV-181 (drug)
Dates
Started 2017-06-14; completion 2019-05-02
Results posted
Not yet

This is a two-part study consisting of Part A (dose regimen finding) followed by Part B (dose expansion). Part A (dose regimen finding) will allow definition of the maximum tolerated dose (MTD) through dose escalation and possible dose interval modification. In Part B (dose expansion), potential therapeutic doses may be studied with SC-004 as monotherapy and SC-004 in combination with ABBV-181 in disease-specific cohorts.

From ClinicalTrials.gov, last updated 2019-05-14. Full record, eligibility and contacts (opens in a new tab)

Industry funding

AbbVie Inc. reported $5,457 in research payments for this study in 2025 (1 payments).

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • City of Hope National Medical Ctr $5,457

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.