Endocrine Therapy With or Without Abemaciclib (LY2835219) Following Surgery in Participants With Breast Cancer
Active, not recruiting · Phase 3 · NCT03155997
Conditions: Breast Cancer
At a glance
- Research payments reported, 2025
- $789,401
- U.S. investigators named
- 103
- Sites paid
- 106
- Planned or actual enrollment
- 5,637
About the trial
- Sponsor
- Eli Lilly and Company (with NSABP Foundation Inc)
- Tested
- Abemaciclib (drug), Standard Adjuvant Endocrine Therapy (drug)
- Dates
- Started 2017-07-12; completion 2029-05
- Results posted
- Yes
The purpose of this study is to evaluate the safety and efficacy of the study drug abemaciclib in participants with high risk, node positive, early stage, hormone receptor positive (HR+), human epidermal receptor 2 negative (HER2-), breast cancer.
From ClinicalTrials.gov, last updated 2026-04-24. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Eli Lilly and Company reported $789,401 in research payments for this study in 2025 (157 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Michael W. Meshad, MD Medical Oncology · Mobile, AL
- Erica Stringer-reasor Hematology & Oncology · Birmingham, AL
- Meghana Bansal Hematology & Oncology · Little Rock, AR
- J T. Beck, M.D., F.A.C.P. Hematology & Oncology · Springdale, AR
- Mazen Khalil, M.D. Hematology & Oncology · Jonesboro, AR
- Aisha Ahmed, M.D. Hematology & Oncology · Tucson, AZ
- Iyad S. Hamarneh, MD Medical Oncology · Prescott, AZ
- Albert G. Wendt, M.D. Medical Oncology · Phoenix, AZ
- Michael Alexander, MD Medical Oncology · Santa Cruz, CA
- Linnea I. Chap, M.D. Hematology & Oncology · Beverly Hills, CA
- Amy J. Chien, M.D. Medical Oncology · San Francisco, CA
- Helen Chow, M.D. Hematology & Oncology · Sacramento, CA
- Erwin Grussie Hematology · Los Angeles, CA
- Steven J. Hager, D.O. Hematology & Oncology · Fresno, CA
- Michael Z. Koontz, MD Internal Medicine · Monterey, CA
- Jennifer M. Suga, M.D. Hematology & Oncology · Vallejo, CA
- Yuan Yuan, M.D., PH.D. Medical Oncology · Pasadena, CA
- Devchand Paul, PHD DO Hematology & Oncology · Denver, CO
- Andrea Dickey Medical Oncology · New Haven, CT
- Walid L. Shaib, M.D. Hematology & Oncology · New Haven, CT
- Elizabeth A. Byron, M.D. Medical Oncology · Palm Springs, FL
- Karen C. Daily Weinstein, D.O. Hematology & Oncology · Gainesville, FL
- Gustavo A. Fonseca, MD Medical Oncology · Lecanto, FL
- Alexander E. Glick, M.D. Medical Oncology · Sarasota, FL
- John M. Hill, MD Family Medicine · Deland, FL
- Rohit R. Rao, M.D Hematology & Oncology · Jacksonville, FL
- Karen B. Russell, MD Hematology & Oncology · Tallahassee, FL
- Aixa Soyano Muller, MD Hematology & Oncology · Tampa, FL
- Grace Wang, M.D. Hematology & Oncology · Miami, FL
- Steven L. Mccune, MD, PHD Hematology & Oncology · Marietta, GA
- Mark A. Taylor, M.D. Hematology & Oncology · Savannah, GA
- Amelia B. Zelnak, MD Hematology & Oncology · Cumming, GA
- Kenneth N. Sumida, M.D. Hematology & Oncology · Honolulu, HI
- Alexander Hantel, MD Hematology & Oncology · Naperville, IL
- Leonard M. Klein Hematology & Oncology · Niles, IL
- Ruta Rao, M.D. Medical Oncology · Chicago, IL
- Annette R. Moore, C.N.P. Nurse Practitioners · Indianapolis, IN
- Meghana Raghavendra, MD Hematology & Oncology · Indianapolis, IN
- Joseph Stilwill, MD Hematology & Oncology · Overland Park, KS
- Elizabeth C. Riley, M.D. Hematology & Oncology · Louisville, KY
- Derrick W. Spell, MD Hematology & Oncology · Baton Rouge, LA
- James J. Rooney, M.D. Hematology & Oncology · Worcester, MA
- Sara M. Tolaney, MD Hematology & Oncology · Boston, MA
- John M. Wallmark, M.D. Hematology & Oncology · Rockville, MD
- Chiara Battelli, MD Hematology & Oncology · Westbrook, ME
- Sarah Sinclair, DO Hematology & Oncology · Brewer, ME
- Lucia A. Garino, M.D. Hematology & Oncology · Coon Rapids, MN
- Matthew P. Goetz, M.D. Medical Oncology · Rochester, MN
- Nicole Jacobi, MD Hematology & Oncology · Coon Rapids, MN
- Tammy H. Young, M.D. Medical Oncology · Jackson, MS
- Mark L. Graham II, M.D. Hematology & Oncology · Cary, NC
- Kirsten M. Leu, M.D. Hematology & Oncology · Omaha, NE
- Peter A. Kaufman, MD Medical Oncology · Lebanon, NH
- Seth D. Cohen, MD Medical Oncology · West Long Branch, NJ
- Steven W. Papish, M.D. Hematology & Oncology · Morristown, NJ
- Eleonora Teplinsky, M.D. Hematology & Oncology · Paramus, NJ
- Sowjanya Reganti, M.D., Hematology & Oncology · Reno, NV
- Lea N. Baer, MD Hematology & Oncology · Stony Brook, NY
- Sarat Chandarlapaty, M.D., PH.D. Medical Oncology · New York, NY
- Dan Costin, MD Hematology & Oncology · White Plains, NY
- Lori Schleicher, MD Hematology & Oncology · New York, NY
- Karen Tedesco, M.D. Hematology & Oncology · Amsterdam, NY
- Timothy Moore, MD Medical Oncology · Columbus, OH
- Cynthia Owusu, MD Hematology & Oncology · Cleveland, OH
- Sunitha Vemulapalli, MD Hematology & Oncology · Canton, OH
- Patrick J. Ward, MD Hematology & Oncology · Cincinnati, OH
- Jay C. Andersen, M.D. Hematology & Oncology · Portland, OR
- Alison K. Conlin, MD Medical Oncology · Portland, OR
- Miho T. Dougherty, M.D. Hematology & Oncology · Eugene, OR
- Apurva Pandey, M.D Medical Oncology · Portland, OR
- Aleksandra S. Sander, M.D. Hematology & Oncology · Medford, OR
- Nicole M. Agostino, DO Medical Oncology · Quakertown, PA
- Nathan Bahary, MD, PHD Specialist · Pittsburgh, PA
- Adam M. Brufsky, MD Specialist · Pittsburgh, PA
- Chanh T. Huynh, MD Hematology & Oncology · York, PA
- Pooja Suresh Hematology & Oncology · Abington, PA
- Isaac E. Alwine, M.D. Hematology & Oncology · Spartanburg, SC
- Rajesh Bajaj, M.D. Hematology & Oncology · Florence, SC
- Allison P. Watson Hematology & Oncology · Sioux Falls, SD
- Brooke E. Daniel, MD Hematology & Oncology · Chattanooga, TN
- Erika P. Hamilton, M.D. Hematology & Oncology · Nashville, TN
- Aleksandar Jankov, MD Hematology & Oncology · Memphis, TN
- Timothy J. Panella, M.D. Medical Oncology · Knoxville, TN
- Robert D. Schumaker, MD Hematology & Oncology · Knoxville, TN
- Eleni Andreopoulou, M.D. Hematology & Oncology · Houston, TX
- Emmalind Aponte, MD Hematology & Oncology · San Antonio, TX
- Kathryn E. Hudson, MD Hematology & Oncology · Austin, TX
- Joyce A. O'shaughnessy, MD Medical Oncology · Dallas, TX
- Julio A. Peguero, M.D Medical Oncology · Corpus Christi, TX
- Paula D. Ryan, MD, PHD Medical Oncology · Shenandoah, TX
- Ines J. Sanchez-rivera, M.D. Medical Oncology · El Paso, TX
- Vibha T. Thomas, M.D. Medical Oncology · Carrollton, TX
- Nisha Unni, M.D. Hematology & Oncology · Dallas, TX
- Stephan D. Kendall, M.D. Medical Oncology · Salt Lake City, UT
- Harry D. Bear, M.D. General Surgery · Richmond, VA
- Michael A. Danso, M.D. Hematology & Oncology · Norfolk, VA
- Mitul Gandhi, M.D. Hematology & Oncology · Manassas, VA
- Amanda L. Gillespie-twardy, M.D. Hematology & Oncology · Roanoke, VA
- William A. Houck III, M.D. Hematology & Oncology · Winchester, VA
- Christopher N. Vaughn, M.D. Hematology & Oncology · Fredericksburg, VA
- Michaela L. Tsai, MD Hematology & Oncology · Seattle, WA
- Sima Ehsani Chimeh, M.D. Hematology & Oncology · Madison, WI
- Jame Abraham, M.D. Hematology & Oncology · Morgantown, WV
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- US Oncology Research LLC $254,712
- Texas Oncology PA $56,184
- Sarah Cannon Research Institute LLC $33,290
- Dana Farber PArtners Cancer Care Inc $26,287
- Florida Cancer Specialists $25,242
- St Josephs Hospital and Medical Center, AZ $23,948
- Research Foundation of State Univ of Ny $23,465
- Ohsu Hospital and Clinics, OR $18,766
- Weill Medical College $11,782
- Maryland Oncology Hematology PA $11,107
- Memorial Sloan-Kettering $10,161
- Fairfax-Northern Virginia $10,086
- Mayo Clinic $9,632
- Biomedical Research Alliance of New York $9,521
- Maine Medical Center $9,170
- Valley Hospital Inc $8,696
- Univ. of Vermont - Fletcher Allen Health Care, VT $8,279
- Northwest Cancer Specialists PC $8,132
- McLeod Regional Medical Center-Pee Dee, SC $7,250
- Baptist Memorial Hospital Tipton, TN $7,121
- Miami Cancer Institute at Baptist Health Inc $6,720
- Arizona Oncology Associates PC Hope $6,127
- Uh Cleveland Medical Center, OH $6,125
- Rocky Mountain Cancer Centers LLP $6,099
- Cleveland Clinic, OH $5,940
- Summit Medical Group $5,901
- University of Hawaii $5,798
- Kaiser Foundation Hospital-Santa Clara, CA $5,764
- University of California Davis Medical Center, CA $5,410
- Highlands Oncology Group PA $5,364
- UCSF Langley Porter Psychiatric Hospital and Clinics, CA $5,361
- St Lukes Health Network Inc, DBA St Lukes University Health, Network $5,255
- Oncology and Hematology Assoc of Sw Virginia Inc $5,184
- Oncology Consultants PA $5,157
- Moffitt Cancer Center $4,975
- Center for Biomedical Research $4,815
- University of Louisville Research Foundation Inc $4,702
- Asante, DBA Asante Rogue Regional $4,584
- Oncology Associates of Oregon PC $4,567
- Shenandoah Oncology, PC $4,410
- Southern Cancer Center $4,221
- Cedars-Sinai Medical Center, CA $4,179
- Virginia Oncology Associates $4,065
- University Health System, Inc, TN $4,035
- UPMC Pinnacle Hospitals, PA $4,011
- Hematology Oncology Associates of Fredericksburg Inc. $3,892
- The University of Texas $3,843
- Community Hospital East, IN $3,708
- Northside Hospital Gwinnett, GA $3,493
- Univ of Pittsburgh Cancer Institute Cancer Srvcs $3,438
- Wellspan Health $3,175
- New York Oncology Hematology PC $3,109
- Swedish Issaquah, WA $3,092
- University of Alabama Hospital, AL $3,057
- Iho Corporation $2,911
- Oncology Hematology Care Clinical Trials LLC $2,888
- Yale University $2,865
- Minnesota Oncology Hematology PA $2,675
- Summit Cancer Care $2,568
- Rush University Medical Center, IL $2,568
- Renown Regional Medical Center, NV $2,543
- Columbus Ccop $2,292
- Aultman Hospital, OH $2,292
- Cancer Car Associates of Fresno Medical Group $2,206
- St Bernards Medical Center, AR $2,076
- Tallahassee Memorial Healthcare, FL $1,815
- University of Florida $1,719
- Providence Portland Medical Center, OR $1,719
- St. Francis Hospital & Health Center $1,719
- Fallon Clinic Inc $1,719
- Illinois Cancer Specialists PC $1,700
- Beverly Hills Cancer Center $1,492
- Allegheny Singer Research Institute $1,490
- Univ of Arizona DBA Arizona Board of Regents $1,304
- Virginia Commonwealth University $1,180
- Edward-Elmhurst Healthcare $1,146
- Mary Bird Perkins Cancer Center $1,146
- Northern Light Eastern Maine Medical Center, ME $1,146
- Waverly Hematology Oncology $1,112
- Deaconess Medical Center, WA $849
- Spartanburg Regional $849
- Sanford Research Usd $849
- Nw Ga Oncology Centers PC $765
- Mayo Clinic Jacksonville $711
- Thomas Jefferson University $573
- Monterey Bay Oncology A Med Corp, DBA PAcific Cancer Care $573
- Providence Health System $573
- Newark Beth Israel Medical Center, NJ $573
- Jackson Oncology Associates PLLC $573
- The Nebraska Methodist Hospital, NE $539
- Brain Matters Research Inc $329
- Regents of the University of Colorado $175
- Dent Neurosciences Research Center Inc $164
- Southern California Permanente Medical Group $88
- Washington University $77
- University of Chicago $70
- Uci Health-Orange, CA $66
- University of Washington Medical Ctr, WA $55
- Allergy Asthma Immunology of Rochester $55
- Pardee Hospital Henderson County, NC $46
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.