Safety and Tolerability of Open-Label Flexible-dose Brexpiprazole as Maintenance Treatment in Adolescents With Schizophrenia
Completed · Phase 3 · NCT03238326
Conditions: Schizophrenia
At a glance
- Research payments reported, 2025
- $32,834
- U.S. investigators named
- 10
- Sites paid
- 10
- Planned or actual enrollment
- 295
About the trial
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc. (with H. Lundbeck A/S)
- Tested
- Brexpiprazole (drug)
- Dates
- Started 2017-08-23; completion 2025-04-22
- Results posted
- Yes
To further characterize the long-term safety and tolerability of brexpiprazole in adolescents with schizophrenia
From ClinicalTrials.gov, last updated 2026-02-04. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Otsuka Pharmaceutical Development & Commercialization, Inc. reported $32,834 in research payments for this study in 2025 (13 payments).
Products named: Rexulti
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Nelson Handal, M.D. Child & Adolescent Psychiatry · Dothan, AL
- Marina Bussel, M.D Psychiatry · Playa Vista, CA
- Robert A. Riesenberg, MD Psychiatry · Atlanta, GA
- Kashinath G. Yadalam, MD Psychiatry · Lake Charles, LA
- Punitha I. Rathnam, M.D. Psychiatry · Goldsboro, NC
- Rakesh Ranjan Psychiatry · Medina, OH
- Willis Holloway JR., M.D. Psychiatry · Oklahoma City, OK
- Sarah E. Land, D.O. Psychiatry · Tulsa, OK
- James J. Whalen, M.D. Psychiatry · Lincoln, RI
- Humera A. Chowdhary, MD Child & Adolescent Psychiatry · Denton, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- $8,557
- Atlanta Center for Medical Research LLC $6,746
- Punitha Rathnam New Dawn Psychiatric Services PLLC $6,621
- Erg Clinical Research New York PLLC $2,676
- Lake Charles Clinical Trials LLC $2,000
- North Texas Psychiatric Association PA $1,955
- Cutting Edge Research Group $1,805
- Rakesh Ranjan MD & Associates Inc $1,000
- Proscienceresearchgroup LLC $1,000
- Harmonex Inc $399
- Central States Research LLC $75
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.