Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children
Completed · Phase 2 · NCT03339128
Conditions: Irritable Bowel Syndrome
At a glance
- Research payments reported, 2025
- $21,293
- U.S. investigators named
- 16
- Sites paid
- 18
- Planned or actual enrollment
- 272
About the trial
- Sponsor
- AbbVie
- Tested
- Eluxadoline (drug), Placebo (drug)
- Dates
- Started 2017-11-15; completion 2026-08-17
- Results posted
- Not yet
The primary objectives of this study are to explore the therapeutic effect of eluxadoline in treating irritable bowel syndrome with diarrhea (IBS-D) in pediatric participants 6-17 years of age, to evaluate the pharmacokinetics of eluxadoline in pediatric participants with IBS-D, and to evaluate the safety and tolerability of eluxadoline in pediatric participants with IBS-D. Enrollment of 12-17 years old age group is closed, enrollment of the 6-11 years old age group will continue.
From ClinicalTrials.gov, last updated 2026-09-21. Full record, eligibility and contacts (opens in a new tab)
Industry funding
AbbVie Inc. reported $21,293 in research payments for this study in 2025 (21 payments).
Products named: Viberzi
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Jon M. Robert, MD Pediatrics · Hot Springs, AR
- Louis D. Velez, M.D. Gastroenterology · Little Rock, AR
- Mohammad A. Mahmud, MD, MPH, PHD Internal Medicine · Corona, CA
- Inti Fernandez, M.D General Practice · Miami, FL
- Lucky Flores, M.D. Family Medicine · Miami Lakes, FL
- Edgar Gonzalez, M.D General Practice · Miami, FL
- Felix G. Penate, MD Family Medicine · Miami, FL
- Ana Roig-cantisano, MD Adolescent Medicine · Miami, FL
- Phillip W. Nowlin, MD Family Medicine · Carrollton, GA
- John N. Vu, M.D. Family Medicine · Mcdonough, GA
- Joseph M. Buadoo-croffie, MD Pediatric Gastroenterology · Indianapolis, IN
- Gabrielle N. Virgo, MD FAAP Pediatrics · Silver Spring, MD
- Tatyana A. Feldman, M.D. Medical Oncology · Hackensack, NJ
- Shari Rozen, M.D. Family Medicine · Pittsburgh, PA
- Eric Chiou, MD Pediatric Gastroenterology · Houston, TX
- Audra S. Rouster, M.D. Pediatric Gastroenterology · Morgantown, WV
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Kindred Medical Institute for Clini $6,531
- Riley Hospital for Children at Indiana University Health $2,000
- Elligo Health Research Inc $1,731
- Florida Research Center Inc $1,100
- Wellness Clinical Research LLC $1,000
- West Virginia University $930
- Applied Research Center of Arkansas $804
- Baylor College of Medicine $804
- Healthstar Research $804
- South Miami Medical & Research Group Inc $804
- Clinical Research Institute $804
- Valencia Medical and Research Center $804
- Preferred Primary Care Physicians $804
- Treken Primary Care $804
- Certified Research Consultants $469
- Kindred Medical Institute for Clinical Trials LLC $469
- Indiana University Health Center $335
- Elias Research Associates LLC $296
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.