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A Study of Tirzepatide (LY3298176) Once a Week Versus Insulin Glargine Once a Day in Participants With Type 2 Diabetes and Increased Cardiovascular Risk

Completed · Phase 3 · NCT03730662

Conditions: Type 2 Diabetes Mellitus

At a glance

Research payments reported, 2025
$3
U.S. investigators named
1
Sites paid
1
Planned or actual enrollment
2,002

About the trial

Sponsor
Eli Lilly and Company
Tested
Tirzepatide (drug), Insulin Glargine (drug)
Dates
Started 2018-11-20; completion 2021-04-22
Results posted
Yes

The purpose of the trial is to assess the efficacy and safety of tirzepatide taken once a week to insulin glargine taken once daily in participants with type 2 diabetes and increased cardiovascular risk. The study will last about 108 weeks and may include up to 30 visits.

From ClinicalTrials.gov, last updated 2022-02-14. Full record, eligibility and contacts (opens in a new tab)

Industry funding

Eli Lilly and Company reported $3 in research payments for this study in 2025 (1 payments).

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.