Comparison of Anticoagulation With Left Atrial Appendage Closure After AF Ablation
Completed · Not applicable · NCT03795298
Conditions: Atrial Fibrillation
At a glance
- Research payments reported, 2025
- $248,290
- U.S. investigators named
- 53
- Sites paid
- 52
- Planned or actual enrollment
- 1,600
About the trial
- Sponsor
- Boston Scientific Corporation
- Tested
- WATCHMAN FLX Implant (device), Market-approved OAC (drug)
- Dates
- Started 2019-05-20; completion 2024-07-24
- Results posted
- Yes
The primary objective of this study is to determine if left atrial appendage closure with the WATCHMAN FLX Device is a reasonable alternative to oral anticoagulation following percutaneous catheter ablation for high risk patients with non-valvular atrial fibrillation.
From ClinicalTrials.gov, last updated 2025-09-18. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Boston Scientific Corporation reported $248,290 in research payments for this study in 2025 (101 payments).
Products named: Watchman Access System
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Jeffery S. Allison, M.D. Cardiac Electrophysiology · Huntsville, AL
- Anil Rajendra, M.D. Cardiac Electrophysiology · Birmingham, AL
- Devi G. Nair, MD Cardiac Electrophysiology · Jonesboro, AR
- Vijendra Swarup, M.D. Cardiac Electrophysiology · Phoenix, AZ
- Charles A. Athill, M.D. Cardiac Electrophysiology · San Diego, CA
- Douglas N. Gibson, M.D, Cardiology · La Jolla, CA
- Ivan C. Ho, MD Cardiac Electrophysiology · Los Angeles, CA
- Michael Y. Ho, M.D. Internal Medicine · Stanford, CA
- Vivek Iyer, MD Cardiac Electrophysiology · Larkspur, CA
- Christopher Woods, M.D. Cardiac Electrophysiology · Burlingame, CA
- Russell R. Heath, MD Cardiac Electrophysiology · Fort Collins, CO
- Bradley J. Mikaelian, M.D. Cardiac Electrophysiology · Colorado Springs, CO
- Srikanth A. Sundaram, M.D. Cardiac Electrophysiology · Littleton, CO
- James V. Freeman, M.D. Cardiac Electrophysiology · New Haven, CT
- Ahmed F. Osman, MD Cardiac Electrophysiology · Fort Lauderdale, FL
- Saumil R. Oza, M.D. Cardiac Electrophysiology · Jacksonville, FL
- David B. Delurgio, M.D. Cardiac Electrophysiology · Atlanta, GA
- Troy L. Hounshell, D.O. Cardiology · West Des Moines, IA
- Jeffrey J. Heslop, MD Interventional Cardiology · Boise, ID
- Moeen A. Saleem, MD Cardiac Electrophysiology · Naperville, IL
- Mithilesh K. Das, MD Cardiology · Indianapolis, IN
- Jeffrey A. Olson, DO Cardiac Electrophysiology · Indianapolis, IN
- Rakesh Gopinathannair, M.D., M.A. Cardiac Electrophysiology · Overland Park, KS
- Yeruva Veera Madhu M. Reddy, MD Cardiac Electrophysiology · Kansas City, KS
- Ghulam M. Chaudhry, M.D. Cardiac Electrophysiology · Burlington, MA
- Moussa C. Mansour, MD Cardiac Electrophysiology · Boston, MA
- Arfaat M. Khan, M.D. Cardiology · Detroit, MI
- William Michael P. Mellana JR., M.D. Cardiac Electrophysiology · Midland, MI
- Mario Goessl, M.D. Interventional Cardiology · Minneapolis, MN
- Ammar M. Killu, MBBS Cardiology · Rochester, MN
- Alan P. Wimmer, M.D. Cardiac Electrophysiology · Kansas City, MO
- Jonathan P. Piccini SR., M.D., M.H.S. Cardiology · Durham, NC
- Stephen J. Ackerman, MD Cardiac Electrophysiology · Lincoln, NE
- Benjamin D'souza, MD Cardiac Electrophysiology · Cherry Hill, NJ
- Suneet Mittal, M.D. Cardiac Electrophysiology · Paramus, NJ
- Jason Chinitz, MD Student in an Organized Health Care Education/Training Program · New York, NY
- Larry A. Chinitz, M.D. Cardiac Electrophysiology · New York, NY
- Luigi Di Biase, MD, PHD Cardiology · Bronx, NY
- Madhukar Gupta, M.D. Cardiac Electrophysiology · Cincinnati, OH
- Walid I. Saliba, MD Cardiac Electrophysiology · Cleveland, OH
- Carlos E. Sanchez Soto, MD Interventional Cardiology · Columbus, OH
- Sheetal Chandhok, MD Cardiology · Bryn Mawr, PA
- Sandeep Jain Cardiac Electrophysiology · Pittsburgh, PA
- Chinmay P. Patel, MD Cardiology · Lancaster, PA
- Brian T. Schuler, MD Cardiac Electrophysiology · York, PA
- Arvindh Kanagasundram, M.D. Cardiac Electrophysiology · Nashville, TN
- Robert A. Pickett, M.D. Cardiac Electrophysiology · Nashville, TN
- James B. Deville, MD Cardiac Electrophysiology · Plano, TX
- Scott E. Ewing, DO Interventional Cardiology · Fort Worth, TX
- Rodney P. Horton, M.D. Cardiac Electrophysiology · Austin, TX
- Stanislav Weiner, MD Cardiac Electrophysiology · Longview, TX
- Shenjing Li, MD Interventional Cardiology · Vancouver, WA
- Bryan D. Raybuck, M.D. Interventional Cardiology · Morgantown, WV
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Baylor Research Institute $25,846
- Cardiovascular Associates of Marin and San Francisco Medical Group Inc $24,571
- Vanderbilt University Medical Center, TN $14,233
- Massachusetts General Hospital, MA $10,147
- Yale University $8,550
- Mymichigan Medical Center Midland $8,413
- The Feinstein Institute for Medical Research $8,400
- Biomedical Research Alliance of New York $8,190
- Minneapolis Heart Institute Foundation $7,850
- Medical Center of the Rockies $6,847
- Kansas City Cardiac Arrhythmia Research LLC $6,665
- Saint Thomas Health $6,310
- St Vincents Health System $5,978
- Lankenau Institute for Medical Research $5,650
- Mayo Clinic $5,500
- Hospital of Univ of Pennsylvania, PA $5,393
- New York University $5,005
- Scripps Mercy Hospital, CA $4,801
- Ohiohealth Research Institute $4,750
- Memorial Health Systems $4,534
- University of Kansas Medical Center Research Institute Inc $4,395
- Indiana University Health, IN $4,200
- Kaiser Foundation Hospital-Santa Clara, CA $4,000
- Affinity Cardiovascular Specialists LLC $3,800
- Duke University $3,750
- University of Southern California $3,338
- Lahey Clinic Inc $3,150
- Pinnacle Health Cardiovascular Institute $3,000
- Emory University Hospital, GA $2,775
- Wellspan Health $2,750
- St Lukes Hospital of Kansas City, MO $2,750
- University of Pittsburgh Cancer Institute Cancer Services $2,550
- The Valley Hospital Inc $2,465
- Cis Clincal Research Corporation $2,450
- West Virginia University $2,300
- Nair Research LLC $2,291
- Peacehealth $2,125
- Mercyone Des Moines Medical Center, IA $2,061
- Henry Ford Health Hospital, MI $2,000
- Trinity Clinic $1,963
- St Josephs Hospital and Medical Center, AZ $1,500
- Portercare Adventist Health System $1,463
- Nebraska Specialty Network LLC $1,463
- Central Indiana Health System Cardiac Services Inc $1,463
- Sterling Independent Services $1,450
- The Carl and Edyth Lindner Center for Research and Education at The Christ Hospital $1,350
- California PAcific Medical Ctr-Davies Campus Hosp, CA $1,324
- Broward Health Medical Center, FL $750
- Texas Cardiac Arrythmia Research $685
- Saint Alphonsus Regional Medical Center, ID $500
- Cleveland Clinic, OH $500
- Heart Center Inc. $100
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.