Long-term Safety and Efficacy Extension Trial of Bimatoprost SR
Completed · Phase 3 · NCT03891446
Conditions: Open-Angle Glaucoma, Ocular Hypertension
At a glance
- Research payments reported, 2025
- $648,472
- U.S. investigators named
- 33
- Sites paid
- 41
- Planned or actual enrollment
- 455
About the trial
- Sponsor
- AbbVie
- Tested
- Bimatoprost SR (drug), Standard of Care (other)
- Dates
- Started 2019-03-27; completion 2026-06-19
- Results posted
- Not yet
This study will evaluate the long-term safety and efficacy of Bimatoprost Sustained Release (SR) in patients with open-angle glaucoma or ocular hypertension who completed 1 of the 4 Phase 3 Bimatoprost SR studies (192024-091, -092, -093, or -095) and received Bimatoprost SR or who received commercial DURYSTA (Bimatoprost SR) in the open-label Phase 4 ARGOS study (MED-MA-EYE-0648) and completed (or exited early from) the study.
From ClinicalTrials.gov, last updated 2026-07-15. Full record, eligibility and contacts (opens in a new tab)
Industry funding
AbbVie Inc. reported $648,472 in research payments for this study in 2025 (99 payments).
Products named: Durysta
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Sebastian B. Heersink, MD Ophthalmology · Dothan, AL
- John B. Cason, M.D. Ophthalmology · Phoenix, AZ
- Michael J. Depenbusch, M.D. Ophthalmology · Chandler, AZ
- Max C. Kim, MD Ophthalmology · Phoenix, AZ
- Jacob W. Brubaker, M.D. Ophthalmology · Sacramento, CA
- Andrew Camp, MD Ophthalmology · San Diego, CA
- Eran Duzman, M.D. Ophthalmology · Irvine, CA
- Damien F. Goldberg, M.D. Ophthalmology · Torrance, CA
- Daniel Krivoy, M.D. Ophthalmology · Culver City, CA
- James H. Lee, MD Ophthalmology · Colorado Springs, CO
- Ramesh S. Ayyala, M.D. Ophthalmology · Tampa, FL
- Jeffrey H. Levenson, M.D. Ophthalmology · Jacksonville, FL
- Andrew G. Logan, MD Ophthalmology · Tamarac, FL
- Bruce A. Segal, MD Ophthalmology · Delray Beach, FL
- Stephen E. Smith, M.D. Ophthalmology · Fort Myers, FL
- Douglas G. Day, M.D. Ophthalmology · Atlanta, GA
- Ahmad A. Aref, M.D. Ophthalmology · Chicago, IL
- Brennan P. Greene, MD Ophthalmology · Louisville, KY
- Mahdi Basha, D.O. Ophthalmology · Fraser, MI
- Mujtaba A. Qazi, M.D. Ophthalmology · Chesterfield, MO
- James D. Branch, MD Ophthalmology · Winston-salem, NC
- Jitendra Swarup, M.D. Ophthalmology · Elizabeth City, NC
- Lance K. Bergstrom, M.D. Specialist · Fargo, ND
- Eric B. Mann, MD Ophthalmology · Dover, NJ
- Steven R. Sarkisian JR., MD Ophthalmology · Oklahoma City, OK
- William C. Christie, MD Ophthalmology · Cranberry Township, PA
- Christopher M. Spearman, M.D. Ophthalmology · Cranberry Township, PA
- Jeffrey Kammer, MD Ophthalmology · Nashville, TN
- Kundandeep S. Nagi, M.D. Ophthalmology · San Antonio, TX
- Pankajkumar G. Shah, MD Ophthalmology · Mission, TX
- Thomas R. Walters, MD Ophthalmology · Austin, TX
- Jorge L. Campana, M.D. Ophthalmology · Falls Church, VA
- James D. Paauw, M.D. Ophthalmology · Lynchburg, VA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Scott & Christie and Associates $75,086
- Vanderbilt University Medical Center, TN $65,001
- Piedmont Eye Center Inc $54,379
- Retina Associates Psc $33,028
- Levenson Eye Associates Inc $31,746
- University of Illinois Hospital and Clinics, IL $22,408
- Doctrials $18,052
- Colorado Eye Institute $17,684
- Migs Consulting LLC $17,684
- Emerson Clinical Research Institute LLC $17,684
- Angeles Eye Institute $17,684
- Midwest Vision Research Foundation at Pepose Vision Institute $17,684
- Trinity Research Group LLC $17,126
- San Antonio Eye Center $16,580
- University of South Florida Board of Trustees $16,211
- Logan Ophthalmic Research LLC $16,211
- Scott and Christie Eyecare Associates PC $14,067
- Segal Drug Trials $13,728
- Bergstrom Eye and Laser Clinic $13,524
- The Eye Care Institute $13,523
- Fraser Eye Care Center $13,523
- Piedmont Eye Center $13,523
- James D Branch Ophthalmology $13,502
- Levenson Eye Associates $13,500
- Colorado Eye Institute (DBA) $13,235
- Segal Drug Trials Inc $12,807
- Discovery Clinical Trials $12,417
- University of South Florida $10,492
- Eye Associates of North Jersey $10,316
- Midwest Vision Research Foundation $6,006
- Albemarle Eye Center PLLC $4,508
- Keystone Operations LLC $4,421
- Efraim Duzman MD Inc $3,100
- Hamilton Glaucoma Center Shiley Eye Center Ucsd $2,915
- Sacramento Eye Consultants $2,013
- Doc Trials LLC $1,100
- Tulane Universtity $750
- Emerson Clinical Research Institute $568
- Coastal Research Associates LLC $500
- Wolstan and Goldberg Eye Associates $95
- Stephen E Smith MD $90
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.