Pan Tumor Rollover Study
Recruiting · Phase 2 · NCT03899155
Conditions: Cancer
At a glance
- Research payments reported, 2025
- $518,201
- U.S. investigators named
- 28
- Sites paid
- 32
- Planned or actual enrollment
- 1,500
About the trial
- Sponsor
- Bristol-Myers Squibb (with Exelixis, Novartis, Clovis Oncology, Inc., Janssen Pharmaceuticals)
- Tested
- Nivolumab (drug), Ipilimumab (drug), Cabozantinib (drug), Trametinib (drug), Relatlimab (drug), Nivolumab + Relatlimab (drug), Capecitabine (drug), Bevacizumab (drug), Temozolomide (drug), Rucaparib (drug), Daratumumab (drug), Regorafinib (drug), Leucovorin (drug), Fluorouracil (drug), Oxaliplatin (drug), Enzalutamide (drug), Sunitinib (drug), Pemetrexed (drug), Pembrolizumab (drug)
- Dates
- Started 2019-08-09; completion 2029-08-25
- Results posted
- Not yet
Main Objective of this study is to examine long-term safety of nivolumab monotherapy including combinations and other cancer therapies in various tumor types.
From ClinicalTrials.gov, last updated 2026-11-06. Full record, eligibility and contacts (opens in a new tab)
Industry funding
E.r. Squibb & Sons, L.l.c. reported $518,201 in research payments for this study in 2025 (33 payments).
Products named: Opdivo
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Thomas Flaig, MD Hematology & Oncology · Aurora, CO
- Adil Daud, MD Medical Oncology · Tampa, FL
- Sigrun Hallmeyer, MD Hematology & Oncology · Park Ridge, IL
- Shaker R. Dakhil, MD Hematology & Oncology · Wichita, KS
- Chao H. Huang, M.D. Hematology & Oncology · Kansas City, KS
- Jason Chesney, MD Internal Medicine · Louisville, KY
- Michael B. Atkins, M.D. Medical Oncology · Boston, MA
- David A. Reardon Hematology & Oncology · Boston, MA
- Julie R. Brahmer, M.D. Medical Oncology · Baltimore, MD
- Leslie A. Fecher, M.D. Medical Oncology · Ann Arbor, MI
- Jennifer L. Atlas, MD Hematology & Oncology · Charlotte, NC
- April K. Salama, M.D. Internal Medicine · Durham, NC
- Lionel D. Lewis, M.D. Internal Medicine · Lebanon, NH
- Saby George, MD Medical Oncology · Buffalo, NY
- Nikhil I. Khushalani, MD MBBS Medical Oncology · Buffalo, NY
- Ana M. Molina, MD Hematology & Oncology · New York, NY
- Jeffrey Schneider, M.D. Hematology & Oncology · Mineola, NY
- Asrar A. Alahmadi, MD Medical Oncology · Columbus, OH
- Jennifer L. Leddon Hematology & Oncology · Cincinnati, OH
- Patrick J. Ward, MD Hematology & Oncology · Cincinnati, OH
- Samuel J. Kerr, M.D. Hematology & Oncology · Lancaster, PA
- Suresh G. Nair, MD Hematology & Oncology · Allentown, PA
- Melissa Wilson, M.D. Medical Oncology · Easton, PA
- Mirelis Acosta, M.D. Hematology & Oncology · San Juan, PR
- Brian M. Lingerfelt, MD Hematology & Oncology · Charleston, SC
- David R. Spigel, M.D. Medical Oncology · Nashville, TN
- Hussein A. Tawbi, MD Internal Medicine · Houston, TX
- Mark R. Albertini, MD Medical Oncology · Madison, WI
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Moffitt Cancer Center $80,818
- University of Louisville Research Foundation, Inc, $64,948
- NYU Langone Hospitals - Tisch Hospitals Clinical Labs $41,944
- UC Health, University of Cincinnati $38,453
- Fdi Clinical Research $32,962
- Georgetown University $32,438
- Hospital of Univ of Pennsylvania, PA $30,489
- Ohio State University Resear Fo $25,890
- Hematology / Oncology Care, Incorporated $23,100
- Ut MD Anderson Cancer Center $23,010
- Health Research Incorporated $22,486
- Sarah Cannon Research Institute, Llc $16,497
- Johns Hopkins University $14,534
- Rsfpp Orthopedic Charleston Hand Group $10,293
- Dana-Farber Cancer Institute $8,559
- Duke University $8,240
- UCSF Langley Porter Psychiatric Hospital and Clinics, CA $7,718
- Dana Farber Cancer Institute, Inc $6,847
- St. Lukes University Health Network $6,364
- Weill Medical College of Cornell University $4,800
- Oncology Hematology Care Blue Ash $3,500
- Abbott Northwestern Hospital, MN $3,250
- Advocate Christ Hospital & Medical Center, IL $3,000
- Dartmouth-Hitchcock Clinic $1,992
- Lehigh Valley Hospital, PA $1,696
- Carolinas Medical Center-Northeast, NC $1,313
- Cancer Center of Kansas $967
- University of Michigan Health System, MI $879
- Regents of the University of Colorado $473
- Board of Regents of the University of Wisconsin Systems $407
- Kumc Research Institute, Incorporated $215
- Oncology Hematology Care, Inc $120
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.