Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With Psoriasis
Completed · Phase 3 · NCT04036435
Conditions: Psoriasis
At a glance
- Research payments reported, 2025
- $734,367
- U.S. investigators named
- 58
- Sites paid
- 58
- Planned or actual enrollment
- 1,466
About the trial
- Sponsor
- Bristol-Myers Squibb
- Tested
- BMS-986165 (drug), Placebo (drug)
- Dates
- Started 2019-08-12; completion 2026-07-21
- Results posted
- Not yet
The main purpose of this study is to evaluate the long-term safety and efficacy of the drug Deucravacitinib (BMS-986165) in participants who have been previously enrolled in an applicable Phase 3 psoriasis study. In addition, the study includes a vaccine cohort to evaluate whether deucravacitinib impacts the humoral immune response to 2 non-live vaccines, the Pneumovax 23 vaccine (pneumococcus), a T-cell independent vaccine, and the Boostrix vaccine (tetanus toxoid), a T-cell dependent vaccine. Additionally, this vaccine cohort assesses the safety of administering these vaccines to subjects with psoriasis receiving deucravacitinib compared to those receiving a placebo.
From ClinicalTrials.gov, last updated 2026-09-10. Full record, eligibility and contacts (opens in a new tab)
Industry funding
E.r. Squibb & Sons, L.l.c. reported $734,367 in research payments for this study in 2025 (68 payments).
Products named: Sotyktu
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Boni Elewski Dermatology · Birmingham, AL
- James Krell Dermatology · Birmingham, AL
- Sandra M. Johnson, MD Dermatology · Fort Smith, AR
- Dowling B. Stough IV, MD Dermatology · Hot Springs, AR
- Sadra S. Jazayeri, MD Dermatology · Phoenix, AZ
- Louise A. Taber, M.D. Internal Medicine · Phoenix, AZ
- Stephen W. Halpern, MD Cardiology · Santa Rosa, CA
- Tissa R. Hata, M.D. Dermatology · San Diego, CA
- Shahram Jacobs, M.D. Internal Medicine · Encino, CA
- Vivian Laquer, M.D. Dermatology · Irvine, CA
- Natasha Mesinkovska, M.D. PH.D. Dermatology · Mission Viejo, CA
- Walter K. Nahm, M.D., PHD. Dermatology · San Diego, CA
- Howard L. Sofen, M.D. Dermatology · Los Angeles, CA
- Bruce Torkan, M.D. General Practice · Los Angeles, CA
- Paul S. Yamauchi, M.D., PHD Dermatology · Santa Monica, CA
- David M. Radin, MD Internal Medicine · Stamford, CT
- Idalia A. Acosta, M.D. General Practice · Miami, FL
- Eddie Armas, MD General Practice · South Miami, FL
- Jose F. Cardona, M.D. General Practice · Miami, FL
- Vicente Chavarria, M.D. Allergy & Immunology · Miami, FL
- Yamirka Duardo-guerra, M.D. Family Medicine · Miami, FL
- Ann M. Reed, D.O. Dermatology · Boca Raton, FL
- David A. Rodriguez, M D Specialist · Miami, FL
- Matthew B. Zook, MD, PHD Dermatology · St Petersburg, FL
- Mark A. Turner, MD Family Medicine · Meridian, ID
- Vivianne C. Beyer, M.D. Dermatology · Springfield, IL
- Philip B. Gorelick, MD Neurology · Chicago, IL
- Scott T. Guenthner, MD Dermatology · Greenwood, IN
- Holly L. Hake-harris, MD Dermatology · South Bend, IN
- Jamie L. Mull, MD Dermatology · Evansville, IN
- Leon H. Kircik, MD Dermatology · Lousiville, KY
- Shondra L. Smith, MD Dermatology · Lake Charles, LA
- Jeffrey M. Sobell, MD Dermatology · Chestnut Hill, MA
- Steven E. Kempers, M.D. Specialist · Fridley, MN
- Akgun Ince, M.D. Rheumatology · Saint Louis, MO
- Rosalyn George, M.D. Dermatology · Wilmington, NC
- Abel D. Jarell, MD Dermatology · Portsmouth, NH
- Jerry Bagel, MD Dermatology · East Windsor, NJ
- Holly E. Kanavy, D.O. Dermatology · Bronx, NY
- Saakshi Khattri, MD Dermatology · New York, NY
- Benjamin A. Bogucki, M.D. Dermatology · Columbus, OH
- Cathy A. Greiwe, M.D. Family Medicine · Columbus, OH
- Robert M. Westcott, M.D. Family Medicine · Lindsay, OK
- Benjamin D. Ehst, M.D., PH.D. Dermatology · Portland, OR
- Phoebe Rich, MD Specialist · Portland, OR
- Timothy Patton Specialist · Pittsburgh, PA
- Gregorio A. Cortes-maisonet, MD General Practice · San Juan, PR
- John M. Humeniuk, M.D., LLC Dermatology · Greenville, SC
- Rica Santiago, M.D Internal Medicine · Mt Pleasant, SC
- Todd E. Schlesinger, M.D. Dermatology · Charleston, SC
- Richard L. Beasley, MD Internal Medicine · Rapid City, SD
- John C. Browning, MD Dermatology · San Antonio, TX
- Steven A. Davis, MD Dermatology · San Antonio, TX
- Patricia C. Lee, M.D. Dermatology · Webster, TX
- Ross C. Radusky, M.D. Dermatology · Dallas, TX
- Craig F. Teller, M.D. Dermatology · Bellaire, TX
- Stephen K. Tyring, MD PHD Dermatology · Webster, TX
- Scott E. Miller, MD Cardiology · Charleston, WV
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- $129,043
- La Universal Research Center Inc $41,913
- Rlb MD PC $41,095
- Well Pharma Medical Research $36,688
- Gcm Medical Group $36,442
- Dermatology Research Associates $34,802
- Alliance Dermatology and Mohs Center $34,423
- Miami Dade Medical Research Institute $21,828
- Oregon Medical Research Center $17,758
- Biomedical Research Alliance of New York, Llc $16,919
- Center for Clinical Studies $16,794
- Clinedge $15,127
- Northbay Clinical Research $13,694
- Springfield Clinic Main Campus East $13,650
- Academic Alliance in Dermatology $13,569
- Dermatology Clinical Research Center of San Antonio $13,281
- Total Skin and Beauty Dermatology Center PC $12,340
- Palm Harbor Dermatology $11,671
- Clinical Research Advantage, Incorporated $11,639
- Shahram Jacobs MD $11,583
- Skin Care Research, Llc $10,873
- Johnson Dermatology $10,397
- Associated Skin Care Specialists $9,808
- Clinohio Research Services $8,881
- Interspond, Llc $8,600
- Deaconess Clinc Inc $8,373
- Clinical Research Center of the Carolinas $7,963
- Arizona Research Center $7,441
- Arthritis Consultants, Inc $7,424
- San Marcus Research Clinic, Inc $7,183
- Indago Research and Health Center, Inc $6,537
- Dermatology and Advanced Aesthetics $5,904
- Burke Pharmaceutical Research $5,681
- University of California San Diego $5,476
- University of Alabama Hospital, AL $4,646
- Tufts Medical Center, MA $4,541
- Coastal Carolina Res Center $4,322
- Bellaire Dermatology $4,305
- Ora $4,121
- Qcare Site Services Inc $4,113
- University Clinical Trials $4,003
- Phoebe Rich Dermatology $3,977
- Clinical Science Institute $3,937
- Mount Sinai School of Medicine $3,882
- The Indiana Clinical Trials Center $3,748
- Uci Health Fountain Valley $3,494
- Wilmington Dermatology Center $3,416
- Schweiger Dermatology and Allergy East Windsor $3,403
- Alsa Research, Llc $3,150
- Velocity Clinical Research $3,000
- Unity Clinical Research $2,833
- University of Pittsburgh Physicians $2,675
- Activmed Practices and Research, Inc $2,500
- Texas Dermatology and Laser Specialists $2,174
- Advanced Clinical Research Incorporated $2,010
- Philip B Gorelick MD Llc $1,984
- First Oc Dermatology $1,707
- Skin Sciences, PLLC $1,131
- Dermatology Treatment and Research Center $500
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.