Fixed-Dose Trial in Early Parkinson's Disease (PD)
Completed · Phase 3 · NCT04201093
Conditions: Parkinson Disease
At a glance
- Research payments reported, 2025
- $371,849
- U.S. investigators named
- 30
- Sites paid
- 31
- Planned or actual enrollment
- 529
About the trial
- Sponsor
- AbbVie
- Tested
- Tavapadon (drug), Placebo (drug), Tavapadon (drug)
- Dates
- Started 2019-12-13; completion 2024-06-28
- Results posted
- Yes
The purpose of this study is to evaluate the clinical efficacy, safety and pharmacokinetics (PK) of 2 fixed doses of tavapadon and placebo in participants with early PD.
From ClinicalTrials.gov, last updated 2025-07-28. Full record, eligibility and contacts (opens in a new tab)
Industry funding
AbbVie Inc. reported $371,849 in research payments for this study in 2025 (71 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Rohit Dhall, MD Neurology · Phoenix, AZ
- Eric S. Farbman, M.D. Neurology · Fresno, CA
- M. L. Purino, M.D. Neurology · Arcadia, CA
- Michele Tagliati, M.D. Neurology · Los Angeles, CA
- Daniel D. Truong, M.D. Neurology · Fountain Valley, CA
- Rajeev Kumar, MD Neurology · Englewood, CO
- Mark Goldstein, MD Neurology · Atlantis, FL
- Robert Hauser, MD Neurology · Tampa, FL
- Stuart H. Isaacson, MD Neurology · Boca Raton, FL
- Julie B. Schwartzbard, MD Neurology · Aventura, FL
- John C. Morgan, MD Neurology · Augusta, GA
- Christopher G. Goetz, MD Neurology · Chicago, IL
- Rajesh Pahwa, M.D. Neurology · Kansas City, KS
- Samuel A. Frank, M.D. Neurology · Boston, MA
- Michael S. Kleinman, DO Neurology · Scarborough, ME
- Aaron L. Ellenbogen, D.O. Neurology · Farmington Hills, MI
- Jeffrey W. Cooney, MD Neurology · Durham, NC
- James M. Patton, MD Neurology · Asheville, NC
- Zoltan K. Mari, MD Neurology · Las Vegas, NV
- Deepak K. Gupta, M.D. Neurology · New York, NY
- Lawrence W. Elmer, M.D. Neurology · Toledo, OH
- Ariane Park, M.D. Neurology · Gahanna, OH
- Andres Deik Acosta Madiedo, MD Neurology · Philadelphia, PA
- Michael B. Hemphill, MD Hematology & Oncology · Hermitage, TN
- Anthony Nicholas Neurology · Memphis, TN
- Bhupesh H. Dihenia, M.D. Neurology · Lubbock, TX
- Raja Mehanna, MD Neurology · Houston, TX
- William G. Ondo, M.D. Neurology · Houston, TX
- Michael Soileau, MD Neurology · Georgetown, TX
- Karen M. Thomas, DO Neurology · Virginia Beach, VA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- The University of Toledo $42,856
- Rush University Medical Center, IL $37,081
- Cleveland Clinic, OH $34,791
- The Methodist Hospital Research Institute $31,972
- Bhupesh Dihenia MD PA $31,853
- Cenexel Rocky Mountain Clinical Research LLC $22,556
- Mainehealth Maine Medical Center, ME $17,422
- Hospital of Univ of Pennsylvania, PA $14,359
- Roseman Medical Research Institute LLC $13,130
- The University of South Florida Board of Trustees $12,466
- University of Alabama Hospital, AL $11,936
- University of Texas Health Science Center at Houston $11,556
- Elligo Health Research Inc $10,737
- The Ohio State University $9,658
- Duke University $9,012
- Univ. of Vermont - Fletcher Allen Health Care, VT $8,039
- Sentara Leigh Hospital, VA $7,742
- Texas Movement Disorder Specialists $6,799
- Horizon Solutions Inc $6,200
- Augusta University Research Institute Inc $5,285
- Beth Israel Deaconess Medical Center, MA $4,263
- University of Arkansas Medical Sciences, AR $2,815
- Velocity Clinical Research Inc $2,750
- Cedars-Sinai Medical Center, CA $2,710
- Visionary Investigators Network $2,433
- Jem Research LLC $2,335
- Parkinson S Disease and Movement Disorders Center of Boca Raton Inc $2,246
- University of Kansas Medical Center Research Institute Inc $2,205
- Sc3 Research Group Inc $1,700
- $1,454
- Quest Research Institute LLC $1,000
- Parkinsons and Movement Disorder Institute $485
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.