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CapTemY90 for Grade 2/3 NET Liver Metastases

Recruiting · Phase 2 · NCT04339036

Conditions: Neuroendocrine Tumor Grade 2, Neuroendocrine Tumors

At a glance

Research payments reported, 2025
$413,927
U.S. investigators named
1
Sites paid
1
Planned or actual enrollment
70

About the trial

Sponsor
Abramson Cancer Center at Penn Medicine
Tested
Capecitabine Oral Product (drug), Temozolomide Oral Product (drug), transarterial radioembolization (combination_product)
Dates
Started 2021-10-07; completion 2028-07-01
Results posted
Not yet

This is a Phase 2 evaluation of hepatic-progression free survival among patients with Grade 2 liver-dominant NET metastases undergoing combination therapy with CapTem and Y90 radioembolization.The hypothesis is to confirm safety and to assess if disease control is improved relative to expectation from either therapy alone. A Grade 3 arm was added in 2025.

From ClinicalTrials.gov, last updated 2026-10-08. Full record, eligibility and contacts (opens in a new tab)

Industry funding

Sirtex Medical Inc reported $413,927 in research payments for this study in 2025 (2 payments).

Products named: Sir-Spheres Microspheres

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.