CHAMPION-AF Clinical Trial
Active, not recruiting · Not applicable · NCT04394546
Conditions: Atrial Fibrillation, Stroke, Bleeding
At a glance
- Research payments reported, 2025
- $2.3M
- U.S. investigators named
- 97
- Sites paid
- 93
- Planned or actual enrollment
- 3,000
About the trial
- Sponsor
- Boston Scientific Corporation
- Tested
- WATCHMAN FLX LAAC Device (device), Non-Vitamin K Oral Anticoagulant (drug)
- Dates
- Started 2020-10-15; completion 2027-12
- Results posted
- Not yet
The primary objective of this study is to determine if left atrial appendage closure (LAAC) with the WATCHMAN FLX device is a reasonable alternative to non-vitamin K oral anticoagulants in patients with non-valvular atrial fibrillation.
From ClinicalTrials.gov, last updated 2026-10-14. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Boston Scientific Corporation reported $2.3M in research payments for this study in 2025 (952 payments).
Products named: Clinical Trial Product
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Hugh Mcelderry Cardiac Electrophysiology · Birmingham, AL
- Anil Rajendra, M.D. Cardiac Electrophysiology · Birmingham, AL
- Devi G. Nair, MD Cardiac Electrophysiology · Jonesboro, AR
- Marwan M. Bahu, M.D. Cardiac Electrophysiology · Phoenix, AZ
- Vijendra Swarup, M.D. Cardiac Electrophysiology · Phoenix, AZ
- Thomas E. Waggoner I, D.O. Interventional Cardiology · Tucson, AZ
- Joseph Aragon, M.D. Interventional Cardiology · Santa Barbara, CA
- Arash Aryana, M.D. Cardiac Electrophysiology · Sacramento, CA
- Rahul N. Doshi, M.D. Cardiac Electrophysiology · Los Angeles, CA
- Leon A. Feldman, M.D. Cardiac Electrophysiology · Rancho Mirage, CA
- Douglas N. Gibson, M.D, Cardiology · La Jolla, CA
- Jordan C. Kawano, M.D. Cardiology · Santa Monica, CA
- Mehran Moussavian, DO Interventional Cardiology · Chula Vista, CA
- Arun Raghupathy, MD Interventional Cardiology · Larkspur, CA
- Chidambaram (chad) Rammohan, M.D. Interventional Cardiology · Mountain View, CA
- William L. Barry, M.D. Interventional Cardiology · Colorado Springs, CO
- Ganesh S. Venkataraman, M.D. Cardiac Electrophysiology · Lakewood, CO
- Jeptha P. Curtis, MD Cardiology · New Haven, CT
- Manish H. Shah, MD Cardiac Electrophysiology · Washington, DC
- James T. Hopkins, M.D. Cardiology · Newark, DE
- Venkata V. Bavikati, MBBS, MPH Cardiac Electrophysiology · Tallahassee, FL
- Daniel E. Friedman, M.D. Cardiac Electrophysiology · Bradenton, FL
- Neal G. Kavesh, MD Cardiac Electrophysiology · Lakeland, FL
- Ahmed F. Osman, MD Cardiac Electrophysiology · Fort Lauderdale, FL
- Saumil R. Oza, M.D. Cardiac Electrophysiology · Jacksonville, FL
- Ramon Quesada, M.D. Interventional Cardiology · Miami, FL
- Naushad A. Shaik, MD Cardiac Electrophysiology · Kissimmee, FL
- David B. Delurgio, M.D. Cardiac Electrophysiology · Atlanta, GA
- Sandeep K. Goyal, MD Cardiac Electrophysiology · Atlanta, GA
- David W. Newton, MD Cardiac Electrophysiology · Savannah, GA
- Phillip A. Horwitz, MD Interventional Cardiology · Iowa City, IA
- Troy L. Hounshell, D.O. Cardiology · West Des Moines, IA
- Albert C. Lin, M.D. Cardiac Electrophysiology · Chicago, IL
- Bharath Rajagopalan, M.B.,B.S Cardiac Electrophysiology · Springfield, IL
- William H. Spear, M.D. Cardiac Electrophysiology · Evergreen Park, IL
- Samer Abbas, MD Interventional Cardiology · East Chicago, IN
- Saeed R. Shaikh, M.D. Interventional Cardiology · Indianapolis, IN
- Yeruva Veera Madhu M. Reddy, MD Cardiac Electrophysiology · Kansas City, KS
- Kent E. Morris, MD Cardiac Electrophysiology · Louisville, KY
- Bruce G. Hook, M.D. Cardiac Electrophysiology · Burlington, MA
- Sunil Kapur, MD Cardiology · Boston, MA
- Moussa C. Mansour, MD Cardiac Electrophysiology · Boston, MA
- Glenn T. Stokken, M.D. Cardiology · Worcester, MA
- Nam S. Cho, DO Interventional Cardiology · Lansing, MI
- Umesh G. Gowda, M.D. Family Medicine · Rochester, MI
- Ilana B. Kutinsky, DO Cardiac Electrophysiology · Troy, MI
- Stuart W. Adler II, M.D. Cardiac Electrophysiology · Saint Paul, MN
- Mohamad Adnan Alkhouli, M.D. Cardiology · Rochester, MN
- Jacob R. Dutcher, MD Interventional Cardiology · St Cloud, MN
- Joseph C. Lin, M.D. Cardiac Electrophysiology · Minneapolis, MN
- Marat Yanavitski, MD Interventional Cardiology · Saint Paul, MN
- Chetan P. Huded, MD Interventional Cardiology · Kansas City, MO
- James E. Stone JR., M.D. Cardiac Electrophysiology · Tupelo, MS
- Loren P. Budge, MD Cardiac Electrophysiology · Billings, MT
- Oluseun O. Alli, MD Interventional Cardiology · Charlotte, NC
- Steven J. Filby, M.D. Interventional Cardiology · Pinehurst, NC
- Himanshu Agarwal, MD Interventional Cardiology · Omaha, NE
- Jason J. Payne, M.D. Cardiac Electrophysiology · Omaha, NE
- Aaron V. Kaplan, MD Interventional Cardiology · Lebanon, NH
- Jamie H. Kim, MD Cardiac Electrophysiology · Londonderry, NH
- Grant R. Simons, MD Cardiac Electrophysiology · Englewood, NJ
- Farhad Abtahian Interventional Cardiology · Rochester, NY
- Srinivas R. Dukkipati, MD Cardiac Electrophysiology · New York, NY
- Vijay S. Iyer, MD, PHD Cardiology · Amherst, NY
- Joseph H. Levine, M.D. Cardiac Electrophysiology · Roslyn, NY
- Robert J. Sommer, M.D. Cardiology · New York, NY
- Anish K. Amin, M.D. Cardiac Electrophysiology · Columbus, OH
- P K. Ramanathan, MD Interventional Cardiology · Toledo, OH
- Walid I. Saliba, MD Cardiac Electrophysiology · Cleveland, OH
- Carlos E. Sanchez Soto, MD Interventional Cardiology · Columbus, OH
- Brian P. Schwartz, M.D. Interventional Cardiology · Centerville, OH
- Amish J. Desai, MD Interventional Cardiology · Portland, OR
- Sandeep Jain Cardiac Electrophysiology · Pittsburgh, PA
- Chinmay P. Patel, MD Cardiology · Lancaster, PA
- Brian T. Schuler, MD Cardiac Electrophysiology · York, PA
- Frank A. Cuoco JR., MD Cardiac Electrophysiology · Charleston, SC
- Robert A. Leonardi, M.D. Interventional Cardiology · West Columbia, SC
- Loren G. Morgan, MD Interventional Cardiology · Columbia, SC
- Christopher R. Ellis, M.D. Cardiac Electrophysiology · Nashville, TN
- Harish Manyam, MD Cardiac Electrophysiology · Chattanooga, TN
- Apurva O. Badheka, M.D. Interventional Cardiology · Denison, TX
- James B. Deville, MD Cardiac Electrophysiology · Plano, TX
- Jonathan Ginns, MBBS MD Cardiology · Austin, TX
- Rodney P. Horton, M.D. Cardiac Electrophysiology · Austin, TX
- Amir Kashani, MD, MS Interventional Cardiology · Houston, TX
- Mehul B. Patel, MD Interventional Cardiology · College Station, TX
- Javier Roman-gonzalez, M.D. Cardiac Electrophysiology · San Antonio, TX
- Stanislav Weiner, MD Cardiac Electrophysiology · Longview, TX
- Jayanthi N. Koneru, MD Cardiac Electrophysiology · Richmond, VA
- Matthew Sherwood, M.D. Interventional Cardiology · Falls Church, VA
- Sameer Gafoor, MD Interventional Cardiology · Seattle, WA
- Benjamin John, MD Cardiac Electrophysiology · Vancouver, WA
- Mahesh Mulumudi Interventional Cardiology · Everett, WA
- Nasir Shariff, MD Cardiac Electrophysiology · Tacoma, WA
- Jeremiah P. Depta, M.D. Interventional Cardiology · Milwaukee, WI
- Jasbir S. Sra, MD Cardiac Electrophysiology · Milwaukee, WI
- Wissam Gharib, M. D. Interventional Cardiology · Morgantown, WV
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Nair Research LLC $172,851
- Tmc Healthcare $142,360
- St Vincents Health System $87,633
- Cardiovascular Institute of San Diego $86,218
- Eisenhower Health $82,027
- West Houston Area Clinical Trial Consultants LLC $76,840
- Alegent Creighton Clinic $67,686
- Erlanger Health Inc $59,732
- HCA Research Institute LLC $57,347
- University of Kansas Medical Center Research Institute Inc $56,063
- Phoenix Cardiovascular Research Group $53,548
- Lexington County Health Services District Inc $50,998
- Honor Health John C. Lincoln Medical Center, AZ $50,674
- Medstar Health Research Institute $48,429
- Novant Health Huntersville Medical Center, NC $48,171
- Mercyone Des Moines Medical Center, IA $46,903
- Watson Clinic Center for Research Inc $41,529
- Baylor Research Institute $41,382
- Emory University Hospital, GA $41,133
- Uh Cleveland Medical Center, OH $40,202
- St Lukes Hospital of Kansas City, MO $39,164
- University of Iowa Hospital & Clinics, IA $39,075
- Hti Hospital Holdings Inc $34,495
- Advocate Christ Hospital & Medical Center, IL $34,003
- Tallahassee Research Institute Incorporated $33,588
- Cleveland Clinic, OH $31,935
- St Mary-Corwin Hospital, CO $31,841
- Monongalia County General Hospital Company $31,624
- University of Pittsbugh Physicians $28,031
- University of Alabama Hospital, AL $27,680
- Vanderbilt University Medical Center, TN $26,094
- Trustees of Columbia Univ in The City of Ny $25,084
- Piedmont Healthcare $24,085
- M Health Fairview University of Mn Medical Center, MN $23,982
- Pinnacle Health Cardiovascular Institute $22,430
- Bay Area Cardiology Assoc. PA $21,981
- Unehealth $19,463
- Northwestern University $17,018
- Cardiology Associates Research LLC $16,870
- Swedish Medical Center, WA $16,735
- Wellspan Health $16,692
- El Camino Health $16,674
- Rochester General Hospital $16,319
- Franciscan Health Indianapolis $16,094
- Trinity Clinic $15,152
- Norton Healthcare Incorporated $14,584
- Ohiohealth Research Institute $14,466
- Yale University $14,405
- University of Massachusetts $13,375
- Affinity Cardiovascular Specialists LLC $13,218
- Peacehealth $13,129
- Munster Medical Research Foundation $12,623
- St Francis Research and Educational Corporation Inc $12,134
- Adventhealth Orlando, FL $11,837
- Promedica Toledo Hospital $10,872
- Billings Clinic Hospital, MT $10,713
- Christiana Hospital, DE $10,241
- Lahey Clinic Inc $10,065
- Catholic Medical Center $9,947
- Beaumont Hospital - Grosse Pointe, MI $9,565
- Chi Institute for Research and Innovation $9,471
- Mayo Clinic $9,321
- Brigham and Women's Hospital, MA $9,313
- St David S Heart and Vascular PLLC $9,190
- Inova Loudoun Hospital, VA $9,179
- Scripps Mercy Hospital, CA $8,601
- Virginia Commonwealth University $8,569
- Manatee Physician Alliance LLC $7,886
- Providence Health System Southern California $7,698
- Cardiovascular Associates of Marin and San Francisco Medical Group Inc $7,617
- Mary Hitchcock Memorial Hospital, NH $7,268
- Providence Regional Medical Center Everett, WA $6,721
- Massachusetts General Hospital, MA $6,017
- Sparrow Clinical Research Institute $5,882
- Kettering Health Main Campus $5,857
- Lemuel Shattuck Hospital $5,756
- Musc Medical Center, SC $5,369
- Lebonheur Childrens Hospital $5,323
- Broward Health Medical Center, FL $4,940
- Santa Barbara Cottage Hospital, CA $4,904
- Centracare - St. Cloud Hospital, MN $4,534
- Englewood Hospital and Medical Center, NJ $4,489
- Dignity Health Medical Foundation $4,290
- Arizona Cardiovascular Research Foundation $4,259
- Texas Cardiac Arrhythmia Research Foundation $3,683
- Legacy Emanuel Medical Center, OR $3,681
- The Childrens Heart Clinic P A $3,360
- Icahn School of Medicine at Mount Sinai $3,339
- Aurora Research Institute LLC $2,630
- South Texas Cardiovascular Consultants $2,020
- Syntropic Corelab LLC $1,548
- Baptist Hospital of Miami $1,281
- Profound Research LLC $150
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.