Flexible-Dose, Adjunctive Therapy Trial in Adults With Parkinson's Disease With Motor Fluctuations (TEMPO-3)
Completed · Phase 3 · NCT04542499
Conditions: Parkinson Disease
At a glance
- Research payments reported, 2025
- $116,945
- U.S. investigators named
- 16
- Sites paid
- 17
- Planned or actual enrollment
- 507
About the trial
- Sponsor
- AbbVie
- Tested
- Tavapadon (drug), Placebo (drug)
- Dates
- Started 2020-09-23; completion 2024-02-15
- Results posted
- Yes
The purpose of this study is to assess the effect of tavapadon on the change from baseline in total daily hours of "on" time without troublesome dyskinesia in L-Dopa-treated participants with Parkinson's Disease (PD) who are experiencing motor fluctuations.
From ClinicalTrials.gov, last updated 2025-04-04. Full record, eligibility and contacts (opens in a new tab)
Industry funding
AbbVie Inc. reported $116,945 in research payments for this study in 2025 (28 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Perminder Bhatia, MD Neurology · Fresno, CA
- Eric S. Farbman, M.D. Neurology · Fresno, CA
- Daniel D. Truong, M.D. Neurology · Fountain Valley, CA
- Adam J. Wolff, M.D. Neurology · Denver, CO
- Robert Hauser, MD Neurology · Tampa, FL
- Wm D. Honeycutt, M.D. Specialist · Maitland, FL
- Sonia K. Kalirao, MD Neurology · Coral Springs, FL
- Christopher G. Goetz, MD Neurology · Chicago, IL
- Aaron L. Ellenbogen, D.O. Neurology · Farmington Hills, MI
- Peter A. Lewitt, M.D. Neurology · West Bloomfield, MI
- Benjamin L. Walter, MD Neurology · Cleveland, OH
- Raja Mehanna, MD Neurology · Houston, TX
- Elizabeth L. Peckham, D.O. Neurology · Round Rock, TX
- Arjun Tarakad Neurology · Houston, TX
- Matthew S. Boyce, M.D. Neurology · Richmond, VA
- Leslie J. Cloud, MD Neurology · Richmond, VA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Healthcare Innovations Institute LLC $31,007
- Central Texas Neurology Consultants $21,605
- Denver Neurological Research LLC $10,000
- Roseman Medical Research Institute LLC $9,000
- Neuro-Pain Medical Center Inc $8,565
- Virginia Commonwealth University $7,946
- Cleveland Clinic, OH $7,298
- Baylor College of Medicine $6,762
- $2,870
- Neurology Associates PA $2,344
- Interspond LLC $2,248
- University of Texas Health Science Center at Houston $1,745
- Horizon Solutions Inc $1,527
- Henrico Doctors Neurology Associates LLC $1,298
- Henry Ford Health Hospital, MI $1,154
- Rush University Medical Center, IL $977
- Parkinsons and Movement Disorder Institute $550
- The University of South Florida Board of Trustees $50
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.