Delivery SSO2 Therapy for 60 Min in Anterior MI Patients With PCI ≤ 6 Hours of Symptoms Onset Compared to Standard.
Terminated · Not applicable · NCT04743245
Conditions: Acute Myocardial Infarction, STEMI
At a glance
- Research payments reported, 2025
- $63,428
- U.S. investigators named
- 5
- Sites paid
- 7
- Planned or actual enrollment
- 17
About the trial
- Sponsor
- TherOx
- Tested
- TherOx DownStream System (device), PCI (device)
- Dates
- Started 2022-08-02; completion 2026-04-10
- Results posted
- Not yet
A multi-center randomized post-approval evaluation of delivery of intracoronary hyperoxemic supersaturated Oxygen therapy for 60 minutes in anterior AMI patients with successful reperfusion (via PCI) within 6 hours after onset of symptoms compared to standard therapy
From ClinicalTrials.gov, last updated 2026-05-29. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Zoll Circulation Inc reported $63,428 in research payments for this study in 2025 (17 payments).
Products named: Temperature Management System Start-Up Kit, Downstream Cartridge, Catheter, Temperature Management System, Therox Ds2 Console
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Michael Butler, MD Interventional Cardiology · Huntsville, AL
- Hal S. Wasserman, M.D. Interventional Cardiology · Danbury, CT
- Amir S. Lotfi, MD Interventional Cardiology · Springfield, MA
- James Blankenship, M.D. Interventional Cardiology · Albuquerque, NM
- Nainesh C. Patel, M.D. Interventional Cardiology · Allentown, PA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.