Study To Assess Adverse Events and Change in Disease Activity Of 24-hour Continuous Subcutaneous Infusion Of ABBV-951 In Adult Participants With Advanced Parkinson's Disease
Completed · Phase 3 · NCT04750226
Conditions: Parkinson's Disease (PD)
At a glance
- Research payments reported, 2025
- $488,890
- U.S. investigators named
- 27
- Sites paid
- 34
- Planned or actual enrollment
- 118
About the trial
- Sponsor
- AbbVie
- Tested
- ABBV-951 (drug)
- Dates
- Started 2021-02-18; completion 2026-04-27
- Results posted
- Not yet
Parkinson's disease (PD) is a neurological condition, which affects the brain. PD gets worse over time, but how quickly it progresses varies a lot from person to person. Some symptoms of PD are tremors, stiffness, and slowness of movement. This study will assess how safe and effective ABBV-951 is in adult participants with PD. Adverse events and change in disease activity is evaluated. ABBV-951 is an investigational (unapproved) drug containing Levodopa Phosphate/Carbidopa Phosphate (LDP/CDP) given as an infusion under the skin for the treatment of Parkinson's Disease. Adult participants with advanced PD and who have completed M15-736 or M20-339 study will be enrolled. Approximately 130 p…
From ClinicalTrials.gov, last updated 2026-06-01. Full record, eligibility and contacts (opens in a new tab)
Industry funding
AbbVie Inc. reported $488,890 in research payments for this study in 2025 (106 payments).
Products named: Vyalev
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Nicki Niemann, M.D. Neurology · Phoenix, AZ
- Perminder Bhatia, MD Neurology · Fresno, CA
- Khashayar Dashtipour, M.D. Neurology · Loma Linda, CA
- Artin Minaeian, M.D. Neurology · Glendale, CA
- Paul K. Brownstone, M.D. Clinical Pharmacology · Boulder, CO
- Andrew S. Kern, M.D., M.S. Neurology · Aurora, CO
- Rajeev Kumar, MD Neurology · Englewood, CO
- Meagen R. Salinas, MD Neurology · Englewood, CO
- Adam J. Wolff, M.D. Neurology · Denver, CO
- Fernando Pagan Neurology · Washington, DC
- Robert Hauser, MD Neurology · Tampa, FL
- Neepa J. Patel, MD Neurology · Chicago, IL
- Tao Xie Neurology · Chicago, IL
- Irene Litvan, M.D. Neurology · Louisville, KY
- Anna D. Hohler, MD Neurology · Brockton, MA
- Karl N. Knights, M.D. Neurology · Kansas City, MO
- Ritesh Ramdhani, M.D. Specialist · New York, NY
- Kevin J. Klos, MD Neurosurgery · Tulsa, OK
- Tsao Wei Liang, M.D. Neurology · Philadelphia, PA
- Meredith A. Spindler, MD Neurology · Philadelphia, PA
- Daniel O. Claassen, M.D. Neurology · Nashville, TN
- Andrew B. Giritharan, MD Neurology · Nashville, TN
- Harpaul S. Gill, MD Neurology · Cypress, TX
- Michael Soileau, MD Neurology · Georgetown, TX
- Paolo M. Moretti, MD Neurology · Salt Lake City, UT
- Jason L. Aldred, M.D. Neurology · Spokane, WA
- Jill K. Baird, M.D. Neurology · Vancouver, WA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Regents of the University of California the $87,668
- Neuropain Medical Center $66,844
- Feinstein Institute for $53,986
- University of South Florida $40,249
- University of Colorado Denver School of Medicine $29,736
- Georgetown University $23,690
- Bmc Community Hospital Corp II $19,320
- University of Utah Hospital and Clinics, UT $19,076
- Vanderbilt University Medical Center, TN $14,992
- Gill Neuroscience $14,947
- University of Chicago $14,220
- Texas Movement Disorder Specialists PLLC $13,832
- Cenexel Rocky Mountain Clinical $13,629
- St Josephs Hospital and Medical Center, AZ $13,622
- Rush University Medical Center, IL $13,603
- Inland Northwest Research LLC $10,339
- Legacy Emanuel Medical Center, OR $6,732
- Loma Linda University Health $4,930
- Hospital of Univ of Pennsylvania, PA $4,756
- Sc3 Research - PAsadena $3,600
- Horizon Clinical Research Group $2,257
- University of South Florida Board of Trustees $1,657
- Boston Medical Center-Brighton, MA $1,657
- University of California San Diego Jacobs Medical Center $1,657
- Feinstein Institutes for Medical Research $1,657
- Movement Disorder Clinic of Oklahoma the $1,657
- St Lukes Hospital of Kansas City, MO $1,657
- Texas Movement Disorder Specialists $1,657
- Alpine Clinical Research Center Inc $1,400
- Ucm Emergency Department Outpatient Pharmacy $1,243
- Denver Neurological Research $828
- Neuro PAin Medical Center $828
- Sidney Kimmel Medical College at Thomas Jefferson University $690
- Alpine Clinical Research Center $276
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.