A Study of BGB-11417 in Participants With Myeloid Malignancies
Recruiting · Phase 1, Phase 2 · NCT04771130
Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasm
At a glance
- Research payments reported, 2025
- $576,303
- U.S. investigators named
- 5
- Sites paid
- 8
- Planned or actual enrollment
- 260
About the trial
- Sponsor
- BeOne Medicines
- Tested
- BGB-11417 (drug), Azacitidine (drug), Posaconazole (drug), BGB-11417 (drug), BGB-11417 (drug)
- Dates
- Started 2021-05-24; completion 2028-08-31
- Results posted
- Not yet
The study will determine the safety, tolerability, recommended Phase 2 dose (RP2D) and preliminary efficacy of BGB-11417 as monotherapy and in combination with azacitidine in participants with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)or MDS/myeloproliferative neoplasm (MPN) .
From ClinicalTrials.gov, last updated 2026-09-14. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Beone Medicines USA, Inc. reported $576,303 in research payments for this study in 2025 (90 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Paul B. Koller, M.D. Hematology · Duarte, CA
- David Swoboda, MD Hematology & Oncology · Tampa, FL
- Jingzhou Hou Hematology & Oncology · Pittsburgh, PA
- Courtney D. Dinardo, MD Hematology & Oncology · Houston, TX
- Guru Subramanian Guru Murthy, M.D Hematology & Oncology · Milwaukee, WI
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- The Medical College of Wisconsin, Inc. $232,027
- UPMC Cancer Centers $176,989
- The Medical College of Wisconsin $50,426
- City of Hope National Medical Ctr $41,076
- Ut MD Anderson Cancer Center $33,207
- Tampa General Hospital, FL $26,163
- Tampa General Hospital $8,207
- Florida Cancer Specialists & Research Institute, LLC $8,207
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.