Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease
Enrolling by invitation · Phase 3 · NCT04905693
Conditions: Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease, Progressive Pulmonary Fibrosis
At a glance
- Research payments reported, 2025
- $4.8M
- U.S. investigators named
- 87
- Sites paid
- 81
- Planned or actual enrollment
- 1,850
About the trial
- Sponsor
- United Therapeutics
- Tested
- Inhaled Treprostinil (drug), Treprostinil Ultrasonic Nebulizer (device)
- Dates
- Started 2022-09-06; completion 2029-12
- Results posted
- Not yet
Study RIN-PF-302 is designed to evaluate the long-term safety and tolerability of inhaled treprostinil in subjects with idiopathic pulmonary fibrosis or progressive pulmonary fibrosis.
From ClinicalTrials.gov, last updated 2026-10-19. Full record, eligibility and contacts (opens in a new tab)
Industry funding
United Therapeutics Corporation reported $4.8M in research payments for this study in 2025 (1,439 payments).
Products named: Tyvaso
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Tejaswini Kulkarni Pulmonology · Birmingham, AL
- Shehabaldin Alqalyoobi, M.D. Critical Care Medicine · Scottsdale, AZ
- Sachin Chaudhary, MD General Acute Care Hospital · Tucson, AZ
- Rajat Walia, MD Pulmonology · Phoenix, AZ
- Ayad M. Gharghoury, M.D. Pulmonology · Yucca Valley, CA
- Jeffrey A. Golden, MD Pulmonology · San Francisco, CA
- Ryan M. Klein, MD Internal Medicine · Newport Beach, CA
- Rishi Raj, M.D. Critical Care Medicine · Stanford, CA
- Namita Sood, M.D. Pulmonology · Sacramento, CA
- Ziad Tannous, MD Pulmonology · Palm Springs, CA
- Stephen S. Weigt, MD Pulmonology · Los Angeles, CA
- Bassam Yaghmour, M.D. Critical Care Medicine · Orange, CA
- Gordon L. Yung, M.D. Pulmonology · San Diego, CA
- Joshua J. Solomon, MD Pulmonology · Denver, CO
- Sashi Adigopula, M.D. Heart Failure & Transplant Cardiology · Fort Myers, FL
- Ala T. Ahmad, M.D. Critical Care Medicine · St Petersburg, FL
- Debabrata Bandyopadhyay, MD Critical Care Medicine · Orlando, FL
- Harish Bhaskar, MD Pulmonology · Jacksonville, FL
- Ibrahim Faruqi, MD Critical Care Medicine · Gainesville, FL
- Augustine Lee, MD Pulmonology · Jacksonville, FL
- Jinesh Mehta, M.D. Pulmonology · Weston, FL
- Syed I. Mobin, M.D. Pulmonology · Orlando, FL
- Santosh M. Nair, MD Hematology & Oncology · Orange City, FL
- Vandana Seeram, M.D. Critical Care Medicine · Jacksonville, FL
- Amy H. Case, MD Pulmonology · Austell, GA
- Srihari Veeraraghavan, M.D. Pulmonology · Atlanta, GA
- Bradford Bemiss, MD Pulmonology · Maywood, IL
- Jane Dematte Damico, MD Pulmonology · Chicago, IL
- Daniel Dilling, MD Critical Care Medicine · Maywood, IL
- Sahil M. Pandya, M.D. Pulmonology · Kansas City, KS
- John W. Mcconnell, M.D. Pulmonology · Louisville, KY
- Mohamed Saad, MD Pulmonology · Louisville, KY
- Sally A. Suliman, M.D Pulmonology · Louisville, KY
- Afsana Asharaf, MD Pulmonology · Shreveport, LA
- Amita Krishnan, M.D. Pulmonology · New Orleans, LA
- Joseph Lasky, MD Pulmonology · New Orleans, LA
- Gautam George, M.D. Pulmonology · Cambridge, MA
- Leo C. Ginns, MD Pulmonology · Boston, MA
- Nicholas S. Hill, MD Pulmonology · Boston, MA
- Gary M. Hunninghake, MD Pulmonology · Boston, MA
- Jonathan B. Cohen, M.D. Internal Medicine · Rockville, MD
- Sonye K. Danoff, M.D. Pulmonology · Baltimore, MD
- Elizabeth A. Belloli, M.D. Pulmonology · Ann Arbor, MI
- Teng Moua, M.D. Pulmonology · Rochester, MN
- Neil Ettinger, MD Pulmonology · Chesterfield, MO
- Tonya D. Russell, MD Pulmonology · Saint Louis, MO
- Mark B. Yagan, M.D. Pulmonology · Kansas City, MO
- Andrew M. Wilhelm, D.O. Pulmonology · Jackson, MS
- Benjamin J. Bregman, M.D. Critical Care Medicine · Winston Salem, NC
- Lake D. Morrison, MD Pulmonology · Durham, NC
- Murali Ramaswamy, MD FAAFP Pulmonology · Greensboro, NC
- Lee Morrow, M.D. Pulmonology · Omaha, NE
- Nour A. Ass'ad, M.D. Internal Medicine · Albuquerque, NM
- Alpa G. Desai, M.D. Pulmonology · Stony Brook, NY
- Robert M. Kottmann, M.D. Pulmonology · Rochester, NY
- Ali Mansour, MD Internal Medicine · Bronx, NY
- Anna Podolanczuk, M.D. Critical Care Medicine · New York, NY
- Arunabh Talwar, MD Pulmonology · New Hyde Park, NY
- Nitin Y. Bhatt, MD Pulmonology · Columbus, OH
- Nishant Gupta, M.D. Pulmonology · Cincinnati, OH
- Joseph G. Parambil, M.D. Pulmonology · Cleveland, OH
- Jad Kebbe, M.D. Pulmonology · Oklahoma City, OK
- Granthem T. Farr, DO Pulmonology · Portland, OR
- Michaela R. Anderson, M.D. Pulmonology · Philadelphia, PA
- Rebecca Bascom, M.D. Pulmonology · Hershey, PA
- Parth M. Rali, MD Pulmonology · Philadelphia, PA
- Michael B. Denenberg, M.D. Pulmonology · Rock Hill, SC
- Abhinav Gupta, M.D. Critical Care Medicine · Columbia, SC
- Rachana Krishna, M.D. Pulmonology · Charleston, SC
- Justin C. Hewlett, MD Pulmonology · Nashville, TN
- Aaron Milstone, MD Pulmonology · Franklin, TN
- Eric M. Weaver, MD Pulmonology · Knoxville, TN
- Rodeo A. Abrencillo, M.D. Critical Care Medicine · Houston, TX
- Traci N. Adams, MD Pulmonology · Dallas, TX
- Alfredo R. Arauco Brown, M.D. Pulmonology · Weslaco, TX
- Rahat Hussain, MD Internal Medicine · Houston, TX
- Shahrukh A. Kureishy, MD Pulmonology · Mckinney, TX
- Ivan O. Rosas, M.D. Pulmonology · Houston, TX
- Ather J. Siddiqi, MD Pulmonology · The Woodlands, TX
- Yosafe Wakwaya, M.D. Pulmonology · Dallas, TX
- Peter F. Crossno, MD Critical Care Medicine · Murray, UT
- Mary B. Scholand, MD Pulmonology · Salt Lake City, UT
- Shilpa Johri, MD Pulmonology · Richmond, VA
- Christopher S. King, MD Critical Care Medicine · Falls Church, VA
- Hannah C. Mannem, M.D. Pulmonology · Charlottesville, VA
- Mark Barash, D.O. Pulmonology · Milwaukee, WI
- Stephen J. Halliday, M.D., MSCI Pulmonology · Madison, WI
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Inova Loudoun Hospital, VA $161,713
- University of Utah Hospital and Clinics, UT $156,935
- Ronald Reagan UCLA Medical Center, CA $150,286
- Brigham and Women's Hospital, MA $140,768
- The University of Arizona $139,000
- Medical University of South Carolina $136,798
- Mayo Clinic $132,149
- UCSF Langley Porter Psychiatric Hospital and Clinics, CA $124,235
- Cleveland Clinic, OH $112,721
- University of California Davis Medical Center, CA $111,120
- A and A Research Consultants LLC $104,604
- University of Michigan Health System, MI $103,844
- The Washington University $86,936
- The Administrators of the Tulane Educational Fund $86,460
- The University of South Florida $85,447
- Adventist Healthcare Inc $80,700
- Mayo Clinic Jacksonville $79,117
- Kumc Research Institute Inc $78,131
- Biomedical Research Alliance of New York LLC $78,110
- Cleveland Clinic Florida $73,808
- University of Cincinnati $72,702
- Intermountain Health Utah Valley Hospital, UT $69,480
- Northwestern University $69,458
- The Board of Trustees of the Leland Stanford Junior University $68,650
- University of Wisconsin and Visual Sciences $68,603
- Piedmont Healthcare, Inc. $68,591
- The Regents of the University of California $66,286
- Loyola University of Chicago $63,726
- Temple University of the Commonwealth System of Higher Education $60,537
- Baylor Research Institute $60,341
- The University of Texas Southwestern Medical Center $57,959
- University of Florida $57,311
- Pulmonary Assoc of Richmond Inc $57,264
- The Johns Hopkins University $57,095
- The Lung Research Center LLC $55,976
- Beaumont Hospital - Grosse Pointe, MI $54,971
- Norton Healthcare Inc $54,455
- Pulmonix, LLC $52,035
- Thomas Jefferson University $51,708
- University of Oklahoma $50,728
- St Vincents Health System Inc $49,905
- Clinical Research of Rock Hill $49,793
- Southeastern Research Center LLC $49,722
- The University of Texas Health $49,276
- Creighton University $48,698
- Hospital of Univ of Pennsylvania, PA $48,440
- National Jewish Health, CO $47,079
- The Oregon Clinic PC $44,681
- Prisma Health Richland Hospital, SC $42,544
- Baylor College of Medicine $42,363
- Palmtree Clinical Research Inc $42,080
- Pennsylvania State University $41,985
- Renovatio Clinical Consultants LLC $41,580
- The Ohio State University $41,496
- Emory University Hospital, GA $40,349
- Medical College of Wisconsin Inc $39,670
- University of Alabama Hospital, AL $39,602
- East Carolina University $38,816
- Center for Biomedical Research $38,688
- Vanderbilt University Medical Center, TN $38,104
- Central Florida Pulmonary Group P A $37,720
- Community Hospital East, IN $37,252
- University of New Mexico Hsc $33,783
- Coastal Medical Research Institute $33,387
- Duke University Department of Medicine $32,750
- University of Virginia Medical Center, VA $32,170
- Louisiana State University Health $31,412
- Tufts Medical Center, MA $29,757
- St Josephs Hospital and Medical Center, AZ $27,574
- Strong Memorial Hospital, NY $27,046
- Newportnativemd Inc $23,803
- Weill Medical College of Cornell University $22,725
- University of Louisville Research Foundation Inc $20,965
- Louisiana State University Health Sciences Center $20,563
- Clinical Trials Center of Middle Tennessee $20,106
- Metroplex Pulmonary and Sleep Center $17,447
- Massachusetts General Hospital, MA $16,900
- University of Mississippi Med Center, MS $12,712
- St Lukes Hospital of Kansas City, MO $9,150
- The Research Foundation Suny $3,800
- Uci Health-Orange, CA $1,571
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.