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Tazemetostat in Malignant Peripheral Nerve Sheath Tumors

Active, not recruiting · Phase 2 · NCT04917042

Conditions: Peripheral Nerve Sheath Tumor

At a glance

Research payments reported, 2025
$83,100
U.S. investigators named
1
Sites paid
1
Planned or actual enrollment
10

About the trial

Sponsor
University of Florida (with Epizyme, Inc.)
Tested
Tazemetostat (drug)
Dates
Started 2021-08-25; completion 2026-12
Results posted
Yes

This phase 2, open label, single arm study will investigate the use of tazemetostat in patients with recurrent/refractory and/or metastatic malignant peripheral nerve sheath tumors.

From ClinicalTrials.gov, last updated 2026-06-04. Full record, eligibility and contacts (opens in a new tab)

Industry funding

Ipsen Biopharmaceuticals, Inc reported $83,100 in research payments for this study in 2025 (1 payments).

Products named: Tazverik

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • University of Florida Pediatric $83,100

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.