A Study of Zika Vaccine mRNA-1893 in Adult Participants Living in Endemic and Non-Endemic Flavivirus Areas
Completed · Phase 2 · NCT04917861
Conditions: Zika Virus
At a glance
- Research payments reported, 2025
- $384,610
- U.S. investigators named
- 7
- Sites paid
- 8
- Planned or actual enrollment
- 808
About the trial
- Sponsor
- ModernaTX, Inc.
- Tested
- mRNA-1893 (biological), Placebo (biological)
- Dates
- Started 2021-06-07; completion 2024-07-26
- Results posted
- Yes
This clinical study will evaluate the safety, tolerability, and reactogenicity of 2 dose levels of messenger RNA (mRNA)-1893 Zika vaccine in comparison to a placebo control in healthy participants who are flavivirus-seronegative and in participants who are flavivirus-seropositive.
From ClinicalTrials.gov, last updated 2025-09-25. Full record, eligibility and contacts (opens in a new tab)
Industry funding
ModernaTX, Inc. reported $384,610 in research payments for this study in 2025 (45 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Carlos A. Fierro, MD General Practice · Kansas City, KS
- David J. Ensz, M.D. Family Medicine · South Sioux City, NE
- Carmen Colon-tarbal, M.D. Pediatrics · San Juan, PR
- Gregorio A. Cortes-maisonet, MD General Practice · San Juan, PR
- Irma L. Febo, M.D. Specialist · San Juan, PR
- Carlos A. Sariol, MD Family Medicine · San Juan, PR
- William Seger, M.D. Family Medicine · Fort Worth, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Johnson County Clin-Trials $174,807
- Caribbean Medical Research Center $76,895
- Recinto De Ciencias Medicas $49,531
- Gcm Medical Group Psc $38,039
- Lsb Research Group LLC $22,259
- Meridian Clinical Research LLC $14,694
- Gcm Medical Group Psc. $5,038
- Pharmaseek LLC $3,347
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.