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Study of Oral LOXO-338 in Patients With Advanced Blood Cancers

Completed · Phase 1 · NCT05024045

Conditions: Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-cell Marginal Zone, Lymphoma, Non-Hodgkin, Multiple Myeloma, B-cell Lymphoma, Waldenstrom Macroglobulinemia, Lymphoma, Mantle-Cell

At a glance

Research payments reported, 2025
$24,521
U.S. investigators named
2
Sites paid
2
Planned or actual enrollment
27

About the trial

Sponsor
Eli Lilly and Company
Tested
LOXO-338 (drug), Pirtobrutinib (drug)
Dates
Started 2021-09-30; completion 2026-03-02
Results posted
Not yet

The purpose of this study is to find out whether the study drug, LOXO-338, is safe and effective in patients with advanced blood cancer. Patients must have already received standard therapy. The study may last up to approximately 3 years.

From ClinicalTrials.gov, last updated 2026-10-06. Full record, eligibility and contacts (opens in a new tab)

Industry funding

Eli Lilly and Company reported $24,521 in research payments for this study in 2025 (2 payments).

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • City of Hope National Medical Ctr $20,521
  • St. Francis Hospital & Health Center $4,000

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.