Skip to main content

A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures

Recruiting · Phase 3 · NCT05077904

Conditions: Stereotypical Prolonged Seizures

At a glance

Research payments reported, 2025
$740,157
U.S. investigators named
55
Sites paid
99
Planned or actual enrollment
350

About the trial

Sponsor
UCB Biopharma SRL
Tested
Staccato alprazolam (drug), Placebo (other)
Dates
Started 2021-12-07; completion 2027-03-29
Results posted
Not yet

The purpose of the study is to assess the success of a single administration of Staccato alprazolam compared with placebo both in rapidly terminating a seizure episode within 90 seconds and with no recurrence of seizure(s) up to 2 hours after investigational medicinal product (IMP) administration.

From ClinicalTrials.gov, last updated 2026-11-06. Full record, eligibility and contacts (opens in a new tab)

Industry funding

UCB SA reported $740,157 in research payments for this study in 2025 (111 payments).

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Washington University $70,000
  • Pediatric Neurology PA $57,604
  • Mayo Clinic Jacksonville $44,943
  • Boston Medical Center, MA $40,725
  • Vanderbilt University Medical Center, TN $39,834
  • Brigham and Women's Hospital, MA $36,102
  • Altoona Center for Clinical Research $34,508
  • University of Florida $27,004
  • Rancho Research Institute Inc $26,677
  • Lynn Health Science Institute Inc. $23,348
  • Ohsu Hospital and Clinics, OR $23,165
  • Allegheny-Singer Research Institute $21,717
  • Hospital of Univ of Pennsylvania, PA $20,349
  • Cleveland Clinic, OH $19,690
  • University of Utah Hospital and Clinics, UT $18,959
  • Legacy Emanuel Medical Center, OR $18,500
  • New York University $15,456
  • Strong Memorial Hospital, NY $15,296
  • Profound Research Llc $14,834
  • Ezr Research $14,750
  • Ronald Reagan UCLA Medical Center, CA $14,731
  • University of Miami $14,029
  • West Haven VA Medical Center $13,720
  • Northwestern University $13,180
  • Medical Faculty Associates $12,115
  • Xenoscience Inc $9,504
  • Atrium Health Union, NC $8,322
  • Rutgers the State University $8,316
  • The Research Institute at Nationwide Childrens Hospital $7,700
  • Knight Neurology $6,689
  • Valley Health Diabetes Management Program $6,500
  • Clintific Research Inc $5,622
  • Louisiana State University Health $4,402
  • Ochsner Medical Center Acute, LA $3,250
  • Allegheny Singer Research Institute $3,242
  • Robert T. Wechsler, MD, Phd Idaho Comprehensive Epilepsy $2,440
  • Ezr Research, LLC $2,258
  • Le Bonheur Childrens Hospital Foundation $2,100
  • Wcg Clinical $2,046
  • Legacy Medical Group - Neurology at Emanuel $1,919
  • UC San Diego Altman Clinical & Translational Research Institute $1,919
  • Adult and Child Neurology Medical Associates, Inc $1,910
  • Allied Physicians, Inc $1,850
  • Akron Children's Hospital, OH $1,648
  • Northwest Florida Clinical Research Group LLC $1,316
  • Lsu Health Sciences Center $1,014
  • Temple University of the Commonwealth System $560
  • Clinical Trials, Inc. $533
  • Jefferson Cherry Hill Hospital $401
  • University of Pittsburgh Physicians $393
  • UC Irvine Medical Center- Als & Neuromuscular Center $300
  • George Washington University Medical Faculty Associates - Neurology $150
  • Duke University $150
  • Winchester Neurological Consultants $146
  • Rancho Research Institute $136
  • New York University Langone Medical Center $134
  • Child Neurology Consultants of Austin $131
  • Digestive Disease Center $131
  • University of Miami Don Soffer Clinical Research $104
  • Thomas Jefferson University Epilepsy Center $98
  • Northwell Health $98
  • Consultants in Epilepsy and Neurology, PLLC $80
  • Jersey Shore University Medical Center (jsumc) $80
  • University of Pennsylvania $78
  • Northwell Health Lenox Hill $76
  • Perseverance Research Center $70
  • UC Davis Ctsc Clinical Research Center $61
  • Allegheny Health Network - Allegheny Neurological Associates $56
  • Profound Research, Llc $56
  • Xenoscience $56
  • Rutgers Robert Wood Johnson School of Medicine $52
  • University of Florida Jacksonville $52
  • Northwestern Medical Group $52
  • Atrium Health Neurosciences Institute Neurology Charlotte $52
  • Clinical Trials, Inc $40
  • Long Island Jewish Medical $33
  • Southern Illinois University School of Medicine, Neurosciences Institute - Dept of Neurology $28
  • UPMC Montefiore Clinical and Translational Research Center $28
  • University Medical Center New Orleans (lcmc Health) $28
  • Le Bonheur Childrens Hospital Er $28
  • Research Institute of Orlando $28
  • Northwestern Medical Group - Allergy & Immunology Clinic $28
  • Uthealth Houston Mcgovern Med School - Texas Health Institute for Restorative Neurotechnologies $28
  • Northwell Health Lenox Hill - Neurology $28
  • Icahn School of Medicine at Mount Sinai $28
  • University of Rochester Medical Center (urmc) $28
  • Temple University Hospital - Radiation Oncology $28
  • Vanderbilt University Medical Center Radiation Oncology $28
  • Usf Health South Tampa Center for Advanced Healthcare $28
  • Washington University School of Medicine $28
  • Dent Neurologic Institute $28
  • Md Fort Wayne Neurological Center - Neurology $28
  • Mayo Clinic - Jacksonville - Neurology $28
  • Temple University Hospital, PA $26
  • George Washington University Medical Faculty Associates $26
  • Mayo Clinic - Jacksonville $24
  • University of Rochester Medical Center School of Medicine and Dentistry $24
  • Research Institute of Orlando LLC $24

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.