Skip to main content

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

Recruiting · Phase 3 · NCT05125302

Conditions: Migraine

At a glance

Research payments reported, 2025
$1.9M
U.S. investigators named
113
Sites paid
150
Planned or actual enrollment
1,059

About the trial

Sponsor
AbbVie
Tested
Ubrogepant (drug), Placebo-Matching Ubrogepant (drug)
Dates
Started 2022-01-13; completion 2027-05
Results posted
Not yet

Migraine is a common neurological disorder typically characterized by attacks of throbbing, moderate to severe headache, often associated with nausea, vomiting, and sensitivity to light and sound. Migraine is extremely common and disabling in children. The purpose of this study is to evaluate how safe and effective ubrogepant is in the acute treatment of migraine in children and adolescents. Ubrogepant is a drug approved for the acute treatment of migraine in adults. Children and adolescents (aged 6-17 years) with a history of migraine will be enrolled. The study will include 2 cohorts of participants - PK Cohort and Main Study (non-PK cohort). Participants aged 6-11 years in the PK Cohor…

From ClinicalTrials.gov, last updated 2026-09-14. Full record, eligibility and contacts (opens in a new tab)

Industry funding

AbbVie Inc. reported $1.9M in research payments for this study in 2025 (663 payments).

Products named: Ubrelvy

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Advanced Research Center Inc $136,897
  • Frontier Clinical Research LLC $74,023
  • Children's Hospital of Philadelphia, PA $69,912
  • Encore Medical Research of Boynton $68,091
  • Preferred Research PArtners Inc $63,018
  • Access Clinical Trials Inc $62,273
  • Pantheon Clinical Research LLC $61,438
  • Highland Research LLC DBA Highland Clinical Research $60,930
  • Cincinnati Children's Hospital Medical Center, OH $53,609
  • Emerson Clinical Research Institute $51,264
  • Dz1lfo Multi Global Conglomerate Inc DBA Auzmer Research $43,743
  • Clinical Associates of Orlando LLC $42,924
  • Paradigm Clinical Research Centers $40,263
  • Gmg Clinical Research LLC $37,844
  • University of Cincinnati $36,767
  • Rehabilitation and Neurological Services LLC $34,259
  • Providence St Vincent Medical Center, OR $32,821
  • Mind + Neurology Wisconsin Sc $31,149
  • Epic Medical Research $30,027
  • Pediatric Neurology PA $28,065
  • Eastside Therapeutic Resource Inc $26,587
  • Columbus Clinical Services LLC $24,883
  • Minneapolis Clinic of Neurology LTD $24,403
  • Velocity Clinical Research Inc $24,391
  • Neostart Corporation DBA Aga Clinical Trials $24,259
  • Univ of Kentucky Research Found $23,808
  • Patient Priority Clinical Sites LLC $22,805
  • Healthstar Research LLC $20,450
  • Gulfcoast Psychiatric Associates LLC $20,343
  • Encore Medical Research LLC $20,176
  • Ki Health PArtners LLC $19,590
  • Accellacare US Inc $19,584
  • Pivotal Clinical Research & Associates LLC $18,556
  • Relaro Medical Trials LLC $18,345
  • Morristown Medical Center, NJ $18,006
  • Clinical Associates Midwest LLC $17,130
  • Luminous Clinical Research LLC $16,884
  • Amicis Research Center $16,565
  • Adly Thebaud MD PA DBA Medical Research Group of Central Florida $16,403
  • Proven Endpoints LLC $16,216
  • Sante Clinical Research LLC $15,979
  • Clinpoint Trials LLC $15,365
  • Mohamed A Abdel Aziz DBA Cincyscience $15,120
  • Lumos Clinical Research Center LLC $14,625
  • Clinical Research Investigator $14,625
  • Bioscience Research LLC $14,374
  • Road Runner Research LTD $13,723
  • Qcare Site Services Inc $12,954
  • The Univ of Texas at Austin $12,891
  • Tribe Clinical Research LLC $12,769
  • Pioneer Research Solutions Inc $12,703
  • University of South Florida $11,661
  • Encore Medical Research of Weston $11,580
  • Advanced Research Institute Of $11,564
  • Cr Services Acquisition US LLC $11,359
  • Upstate Medical Univeristy $10,704
  • Interspond LLC $9,839
  • Cedar Health Research LLC $9,818
  • Alexian Brothers Health System $9,090
  • Chicago Headache Center & Research $8,977
  • Prime Clinical Research Inc $8,342
  • Gcm Medical Group Psc $8,110
  • Alliance for Multispecialty $7,676
  • Excell Research Inc $7,043
  • City Neurology PLLC DBA Modern Migraine MD $6,612
  • Cenexel Iresearch LLC $6,425
  • Headlands Horizons LLC $6,210
  • Caribbean Medical Research Center $6,158
  • Children's Hospital Colorado, CO $5,981
  • Childrens Hospital of the Kings Daughters $5,506
  • Psychiatric Associates $5,200
  • Dynamed Clinical Research LP $4,693
  • Dent Neurosciences Research $4,370
  • Hope Obrien DBA Headache Center of Hope LLC $4,345
  • Clinical Integrative Research Center of Atlanta $4,155
  • National Clinical Research Inc $3,450
  • Rare Disease Research LLC $3,443
  • Houston Clinical Research $3,218
  • Pmg Research Inc $2,880
  • Elligo Health Research Inc $2,880
  • Healthy Perspectives - Innovative Mental Health Services PLLC $2,731
  • Eclipse Clinical Research $2,500
  • Healthstar Research $2,260
  • Atlas Intermediate LLC $2,151
  • Great Lakes Medical Research LLC $2,030
  • Asclepes Research Centers PC DBA Alliance Research $1,966
  • University of Kentucky College of Medicine $1,790
  • Infinite Research Group LLC $1,540
  • Cenexel Iresearch Atlanta $1,440
  • Auzmer Research $1,440
  • Advanced Research Institute of Miami $1,440
  • Clinpoint Trials $1,440
  • Puerto Rico Health and Wellness Institute LLC $1,440
  • Alliance for Multispecialty Research $1,440
  • Dent Neurologic Institute $1,440
  • Pacific Clinical Research Medical Group $1,440
  • University of South Florida Board of Trustees $1,440
  • Paradigm Clinical Research $1,440
  • Cognitive Clinical Trials LLC $1,440
  • The Research Foundation for The State University of New York $1,440

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.