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Long-term Extension Study to Assess Safety and Tolerability of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Pediatric Participants (Ages 6-17)

Enrolling by invitation · Phase 3 · NCT05127954

Conditions: Migraine

At a glance

Research payments reported, 2025
$1.9M
U.S. investigators named
99
Sites paid
92
Planned or actual enrollment
1,200

About the trial

Sponsor
AbbVie
Tested
Ubrogepant (drug)
Dates
Started 2022-01-14; completion 2028-01
Results posted
Not yet

Migraine is a common neurological disorder typically characterized by attacks of throbbing, moderate to severe headache, often associated with nausea, vomiting, and sensitivity to light and sound. Migraine is extremely common and disabling in children. The purpose of this study is to evaluate long term safety and tolerability of ubrogepant in the acute treatment of migraine in pediatric participants. Ubrogepant is a drug approved for the acute treatment of migraine in adults. Pediatric participants (aged 6-17 years) with a history of migraine will be enrolled. Participants who completed the lead-in Study 3110-305-002, as well as those who were placebo responders and screen failed, will be…

From ClinicalTrials.gov, last updated 2025-07-20. Full record, eligibility and contacts (opens in a new tab)

Industry funding

AbbVie Inc. reported $1.9M in research payments for this study in 2025 (703 payments).

Products named: Ubrelvy

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Pantheon Clinical Research LLC $159,109
  • Advanced Research Center Inc $100,500
  • Access Clinical Trials Inc $94,643
  • Proven Endpoints LLC $71,386
  • Highland Clinical Research $66,065
  • Rehabilitation and Neurological Services LLC $63,231
  • Dz1lfo Multi Global Conglomerate $56,378
  • Accellacare US Inc $50,723
  • Lumos Clinical Research Center LLC $50,405
  • Preferred Research PArtners Inc $49,351
  • Frontier Clinical Research LLC $48,118
  • Advanced Research Institute Of $46,488
  • Patient Priority Clinical Sites LLC $41,953
  • Encore Medical Research LLC $40,974
  • Minneapolis Clinic of Neurology LTD $40,383
  • Encore Medical Research of Boynton $35,336
  • Prime Clinical Research Inc $33,080
  • Emerson Clinical Research Institute $32,387
  • Clinical Associates of Orlando LLC $31,473
  • Dent Neurosciences Research $26,229
  • Neostart Corporation DBA Aga Clinical Trials $24,498
  • Children's Hospital of Philadelphia, PA $23,229
  • My Preferred Research LLC $21,607
  • Morristown Medical Center, NJ $21,575
  • Eastside Therapeutic Resource Inc $21,285
  • Interspond LLC $21,140
  • Epic Medical Research $20,955
  • Healthstar Research LLC $20,900
  • Upstate Medical Univeristy $20,569
  • Road Runner Research LTD $20,363
  • Encore Medical Research of Weston $19,606
  • Gmg Clinical Research LLC $18,897
  • University of South Florida $18,466
  • Univ of Kentucky Research Found $18,354
  • Velocity Clinical Research Inc $18,241
  • Houston Clinical Research Associates $18,238
  • Paradigm Clinical Research Centers $17,834
  • Chicago Headache Center & Research Institute LLC $17,473
  • Pediatric Neurology PA $17,362
  • Sante Clinical Research LLC $17,031
  • Bioscience Research LLC $16,862
  • Puerto Rico Health and Wellness $16,766
  • Cr Services Acquisition US LLC $16,491
  • Qcare Site Services Inc $16,077
  • Amicis Research Center $15,375
  • University of Cincinnati $15,149
  • Relaro Medical Trials LLC $13,103
  • Clinical Associates Midwest LLC $12,640
  • Sunwise Clinical Research LLC $12,424
  • Providence St Vincent Medical Center, OR $12,320
  • Gcm Medical Group Psc $11,294
  • Children's Hospital Colorado, CO $11,202
  • Pioneer Research Solutions Inc $11,025
  • Mind + Neurology Wisconsin Sc $10,951
  • Rare Disease Research LLC $10,604
  • Tribe Clinical Research LLC $10,556
  • Alexian Brothers Health System $10,000
  • Clinpoint Trials LLC $9,511
  • Headache Center of Hope LLC $8,405
  • Cenexel Iresearch LLC $8,405
  • Neuro-Pain Medical Center Inc $8,168
  • Gulfcoast Psychiatric Associates LLC DBA Gulfcoast Clinical Research Center $7,382
  • Cincinnati Children's Hospital Medical Center, OH $7,254
  • City Neurology PLLC $7,100
  • Caribbean Medical Research Center $6,818
  • Pacific Clinical Research Management Group LLC $6,599
  • Columbus Clinical Services LLC $6,598
  • Adly Thebaud MD PA DBA Medical Research Group of Central Florida $6,368
  • Tekton Research Inc $6,242
  • Clinical Integrative Research $5,114
  • Pivotal Clinical Research & Associates LLC $5,001
  • Clinical Research Investigator Group LLC $4,600
  • Cedar Health Research LLC $4,478
  • Mohamed A Abdel Aziz DBA Cincyscience $4,364
  • Infinite Research Group LLC $4,266
  • Alliance for Multispecialty $4,052
  • Coastal Pediatric Research $3,650
  • On-Site Clinical Solutions LLC $3,182
  • Cmrc Headlands LLC $3,047
  • Global Research Holdings LLC DBA Global Research Associates $3,000
  • Aim Trials LLC $2,683
  • National Clinical Research Inc $2,100
  • Atlas Intermediate LLC $1,700
  • Ki Health PArtners LLC $1,500
  • The Center for Clinical Trials Inc $1,500
  • Psychiatric Associates $1,500
  • Velocity Clincial Research Inc $1,433
  • Mcb Clinical Research Center $1,000
  • Healthy Perspectives - Innovative Mental Health Services PLLC $998
  • Northwest Florida Clinical Research $650
  • Cvs Health Clinical Trial Services $600
  • Family Psychiatry of the Woodlands PA $253

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.